Non-invasive Vagus Nerve Stimulation for the Prevention of Migraines
Public ClinicalTrials.gov record NCT03716505. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Multicenter, Double-blind, Parallel, Sham-controlled Study of Non-invasive Vagus Nerve Stimulation for the Prevention of Migraines. (Premium II)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to investigate if the use of gammaCore Sapphire™ device reduces the number of migraines preventatively.
Study identification
- NCT ID
- NCT03716505
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 231 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 2, 2018 (Actual)
- Primary completion
- Sep 9, 2020 (Actual)
- Completion
- Sep 9, 2020 (Actual)
- Last update posted
- Sep 11, 2020
2018 – 2020
United States locations
- U.S. sites
- 30
- U.S. states
- 19
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic | Scottsdale | Arizona | 85259 | — |
| The Research Center of Southern California | Carlsbad | California | 92011 | — |
| Stanford University Medical Center Hoover Pavilion | Palo Alto | California | 94304 | — |
| UCSF Headache Center | San Francisco | California | 94115 | — |
| California Medical Clinic for Headache | Santa Monica | California | 90404 | — |
| Summit Headache and Neurologic Institute, PC | Englewood | Colorado | 80113 | — |
| New England Institute for Neurology and Headache | Stamford | Connecticut | 06905 | — |
| Hartford HealthCare Headache Center | West Hartford | Connecticut | 06107 | — |
| University of Miami, Miller School of Medicine | Miami | Florida | 33136 | — |
| Diamond Headache Clinic | Chicago | Illinois | 60642 | — |
| NorthShore Ambulatory Care Center | Glenview | Illinois | 60026 | — |
| Norton Neurology | Louisville | Kentucky | 40207 | — |
| Crescent City Headache and Neurology Center | Chalmette | Louisiana | 70043 | — |
| Ochsner North Shore Medical Center | Covington | Louisiana | 70433 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215-5400 | — |
| Michigan Head Pain & Neurological Institute (MHNI) | Ann Arbor | Michigan | 48104 | — |
| Headache Neurology Research Institute | Ridgeland | Mississippi | 39157 | — |
| StudyMetrix, LLC | City of Saint Peters | Missouri | 63303 | — |
| Clinvest Research | Springfield | Missouri | 65810 | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03766 | — |
| Dent Neurologic Institute | Amherst | New York | 14226 | — |
| NY Neurology Associates | New York | New York | 10003 | — |
| Island Neurological Associates | Plainview | New York | 11803 | — |
| Montefiore Headache Center | The Bronx | New York | 10461 | — |
| University Hospitals of Cleveland | Cleveland | Ohio | 44106 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| ClinPoint Trials LLC | Waxahachie | Texas | 75165 | — |
| Medstar Georgetown University Hospital | McLean | Virginia | 22101 | — |
| West Virginia University Hospitals - Department of Neurology | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03716505, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 11, 2020 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03716505 live on ClinicalTrials.gov.