DEF-315 Better Accuracy in Ejection Fraction (EF) Assessment With DEFINITY
Public ClinicalTrials.gov record NCT03719612. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Open-Label, Multicenter Trial to Evaluate Ejection Fraction, End-Diastolic and End-Systolic Volumes, by Unenhanced and DEFINITY®-Enhanced 2D-Echo and Magnetic Resonance Imaging
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 3, prospective, open-label, multicenter study to evaluate Left Ventricular Ejection Fraction (LVEF) measurement accuracy and reproducibility of DEFINITY® contrast-enhanced and unenhanced echocardiography as compared with non-contrast cardiac magnetic resonance imaging (CMR) used as the truth standard.
Study identification
- NCT ID
- NCT03719612
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 160 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 28, 2018 (Actual)
- Primary completion
- Jan 9, 2020 (Actual)
- Completion
- Jan 9, 2020 (Actual)
- Last update posted
- Jan 28, 2021
2018 – 2020
United States locations
- U.S. sites
- 15
- U.S. states
- 13
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner University of Arizona Medical Center | Tucson | Arizona | 85724 | — |
| Cedars Sinai | Los Angeles | California | 90048 | — |
| University of California-Irvine | Orange | California | 92868 | — |
| UC San Diego | San Diego | California | 92037 | — |
| Alfieri Cardiology | Wilmington | Delaware | 19803 | — |
| Northwestern Medical Group | Chicago | Illinois | 60611 | — |
| Indiana University | Bloomington | Indiana | 46202 | — |
| Baptist Hospital | Paducah | Kentucky | 42003 | — |
| Mercy Unit Hospital | Coon Rapids | Minnesota | 55433 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45219 | — |
| University of Oklahoma | Oklahoma City | Oklahoma | 73104 | — |
| Oregon Health and Sciences University | Portland | Oregon | 97240 | — |
| Albert Einstein Medical Center | Philadelphia | Pennsylvania | 19412 | — |
| Baylor Scott White Research Institute | Temple | Texas | 76501 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03719612, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 28, 2021 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03719612 live on ClinicalTrials.gov.