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Completed Phase 1 Interventional Accepts healthy volunteers

A Study of LY3372993 in Healthy Participants and Participants With Alzheimer's Disease (AD)

ClinicalTrials.gov ID: NCT03720548

Public ClinicalTrials.gov record NCT03720548. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 7, 2026, 4:42 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Single-Dose and Multiple-Dose, Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY3372993 in Healthy Subjects and Patients With Alzheimer's Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The main purpose of this study is to evaluate the safety and tolerability of LY3372993 in healthy participants and participants with AD. The study will also investigate how much LY3372993 gets into the bloodstream and test the effects of LY3372993 in participants with AD. The study has two parts: * Part A - Healthy participants will receive LY3372993 or placebo. Part A will last up to 17 weeks; * Part B - Participants with AD will receive LY3372993 or placebo. Part B will last about 317 days.

Study identification

NCT ID
NCT03720548
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Eli Lilly and Company
Industry
Enrollment
36 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 85 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 4, 2018
Primary completion
May 13, 2019
Completion
May 13, 2019
Last update posted
Jun 4, 2019

2018 – 2019

United States locations

U.S. sites
11
U.S. states
5
U.S. cities
11
Facility City State ZIP Site status
Collaborative Neuroscience Network - CNS Long Beach California 90806
Covance Clinical Research Inc Daytona Beach Florida 32117
Avail Clinical Research LLC DeLand Florida 32720
MD Clinical Hallandale Florida 33009
BioClinica Inc Orlando Florida 32806
IMIC, Inc. Palmetto Bay Florida 33157
Progressive Medical Research Port Orange Florida 32127
BioClinica Inc The Villages Florida 32162
Atlanta Center of Medical Research Atlanta Georgia 30331
Carolina Phase 1 Research (Wake M3) Raleigh North Carolina 27612
PRA Health Sciences Salt Lake City Utah 84124

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03720548, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 4, 2019 · Synced Sep 7, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03720548 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →