A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCM
Public ClinicalTrials.gov record NCT03723655. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Long-Term Safety Extension Study of Mavacamten (MYK-461) in Adults With Hypertrophic Cardiomyopathy Who Have Completed the MAVERICK-HCM (MYK-461-006) or EXPLORER-HCM (MYK-461-005) Trials (MAVA-LTE)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Approximately 30 sites that enrolled participants in the MAVERICK-HCM (MYK-461-006) study in the United States (US) will initiate this study. Approximately 90 sites that enrolled participants in the EXPLORER-HCM (MYK-461-005) study in the US, Europe, and Israel will initiate this study. Note: Approximately 30 centers overlap between MAVERICK and EXPLORER.
Study identification
- NCT ID
- NCT03723655
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 314 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 27, 2018 (Actual)
- Primary completion
- Jan 16, 2026 (Actual)
- Completion
- Jan 16, 2026 (Actual)
- Last update posted
- Feb 20, 2026
2018 – 2026
United States locations
- U.S. sites
- 31
- U.S. states
- 20
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 0045 | Scottsdale | Arizona | 85259 | — |
| Local Institution - 0058 | Los Angeles | California | 90027 | — |
| Local Institution - 0066 | San Francisco | California | 94143 | — |
| Local Institution - 0063 | Stanford | California | 94305 | — |
| Local Institution - 0043 | New Haven | Connecticut | 06520-8017 | — |
| Local Institution - 0067 | Jacksonville | Florida | 32224 | — |
| Local Institution - 0050 | Chicago | Illinois | 60611 | — |
| Local Institution - 0070 | Indianapolis | Indiana | 46260 | — |
| Local Institution - 0049 | Iowa City | Iowa | 52242 | — |
| Local Institution - 0054 | Boston | Massachusetts | 02115 | — |
| Local Institution - 0051 | Ann Arbor | Michigan | 48109 | — |
| Local Institution - 0074 | Grand Rapids | Michigan | 49503 | — |
| Local Institution - 0048 | St Louis | Missouri | 63110 | — |
| Local Institution - 0060 | New York | New York | 10016 | — |
| Local Institution - 0056 | New York | New York | 10032 | — |
| Local Institution - 0071 | Charlotte | North Carolina | 28204 | — |
| Local Institution - 0047 | Durham | North Carolina | 27710 | — |
| Local Institution - 0052 | Cincinnati | Ohio | 45267 | — |
| Local Institution - 0044 | Portland | Oregon | 97239 | — |
| Local Institution - 0068 | Bethlehem | Pennsylvania | 18015 | — |
| Local Institution - 0046 | Philadelphia | Pennsylvania | 19104 | — |
| Local Institution - 0064 | Pittsburgh | Pennsylvania | 15213 | — |
| Local Institution - 0073 | Memphis | Tennessee | 38104 | — |
| Local Institution - 0061 | Dallas | Texas | 75390 | — |
| Local Institution - 0055 | Houston | Texas | 77030 | — |
| Local Institution - 0057 | Houston | Texas | 77030 | — |
| Local Institution - 0072 | Murray | Utah | 84107-5701 | — |
| Local Institution - 0062 | Salt Lake City | Utah | 84112 | — |
| Local Institution - 0053 | Charlottesville | Virginia | 22903 | — |
| Local Institution - 0059 | Richmond | Virginia | 23298 | — |
| Local Institution - 0065 | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 37 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03723655, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 20, 2026 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03723655 live on ClinicalTrials.gov.