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Not listed Phase 3 Interventional

Zero Degree Head Positioning in Hyperacute Large Artery Ischemic Stroke

ClinicalTrials.gov ID: NCT03728738

Public ClinicalTrials.gov record NCT03728738. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 29, 2026, 12:06 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Placing the head of bed (HOB) at 0-degrees has been shown in small studies to improve blood flow to the brain in patients with ischemic stroke caused by large artery occlusions, thereby reducing stroke symptom worsening. This simple yet potentially impactful intervention has yet to be tested in a large clinical trial in hyperacute large artery ischemic stroke patients, but may provide nurses with a powerful contribution to acute stroke care that is capable of preventing worsening of stroke symptoms and promoting stabilization. Because stroke is the leading cause of preventable long-term disability in adults, this study may show that simple methods such as 0-degree HOB positioning should be considered one of the very first actions taken in the emergent management of acute ischemic stroke patients.

Study identification

NCT ID
NCT03728738
Recruitment status
Not listed
Study type
Interventional
Phase
Phase 3
Lead sponsor
University of Tennessee
Other
Enrollment
182 participants

Conditions and interventions

Interventions

Procedure

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 24, 2018
Primary completion
Jun 29, 2022
Completion
Jun 29, 2023
Last update posted
Mar 30, 2020

2018 – 2023

United States locations

U.S. sites
11
U.S. states
9
U.S. cities
11
Facility City State ZIP Site status
Mobile Infirmary Medical Center Mobile Alabama 36607 Recruiting
Ronald Reagan UCLA Medical Center Los Angeles California 90095 Not yet recruiting
Doctors Medical Center Modesto California 95350 Recruiting
Northwestern Central DuPage Hospital Winfield Illinois 60190 Recruiting
University of Louisville Hospital Louisville Kentucky 40202 Recruiting
Moses Cone Medical Center Greensboro North Carolina 27401 Not yet recruiting
Saint Francis Health System Tulsa Oklahoma 74136 Recruiting
Hershey Medical Center - Penn State Health Hershey Pennsylvania 17033 Recruiting
Methodist University Hospital Memphis Tennessee 38104 Recruiting
Medical City - Fort Worth Fort Worth Texas 76104 Recruiting
Memorial Hermann Hospital Houston Texas 77030 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03728738, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 30, 2020 · Synced Sep 29, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03728738 live on ClinicalTrials.gov.

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