ClinicalTrials.gov record
A Study of Tirzepatide (LY3298176) Once a Week Versus Insulin Glargine Once a Day in Participants With Type 2 Diabetes and Increased Cardiovascular Risk
ClinicalTrials.gov ID: NCT03730662
Public ClinicalTrials.gov record NCT03730662. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy and Safety of LY3298176 Once Weekly Versus Insulin Glargine in Patients With Type 2 Diabetes and Increased Cardiovascular Risk (SURPASS-4)
Study identification
- NCT ID
- NCT03730662
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Eli Lilly and Company
- Industry
- Enrollment
- 2,002 participants
Conditions and interventions
Conditions
Interventions
- Insulin Glargine Drug
- Tirzepatide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 19, 2018
- Primary completion
- Jan 21, 2021
- Completion
- Apr 21, 2021
- Last update posted
- Feb 13, 2022
2018 – 2021
United States locations
- U.S. sites
- 74
- U.S. states
- 27
- U.S. cities
- 71
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Advanced Research Center | Anaheim | California | 92805 | — |
| Valley Clinical Trials, Inc. | Covina | California | 91723 | — |
| Marin Endocrine Associates | Greenbrae | California | 94904 | — |
| National Research Institute | Huntington Park | California | 90255 | — |
| Scripps Whittier Diabetes Institute | La Jolla | California | 92037 | — |
| First Valley Medical Group | Lancaster | California | 93534 | — |
| National Research Institute | Los Angeles | California | 90057 | — |
| Catalina Research Institute, LLC | Montclair | California | 91763 | — |
| Monterey Endocrine & Diabetes Institute, Inc. | Monterey | California | 93940 | — |
| Valley Clinical Trials, Inc. | Northridge | California | 91325 | — |
| Desert Medical Group Inc | Palm Springs | California | 92262 | — |
| Havana Research Institute | Pasadena | California | 91105 | — |
| Western University of Health Sciences | Pomona | California | 91766 | — |
| LCGK Research | San Carlos | California | 94070 | — |
| Olive View Medical Center | Sylmar | California | 91342 | — |
| University Clinical Investigators, Inc. | Tustin | California | 92780 | — |
| Touro University | Vallejo | California | 94592 | — |
| Coastal Metabolic Research Centre | Ventura | California | 93003 | — |
| Diablo Clinical Research | Walnut Creek | California | 94598 | — |
| Chase Medical Research, LLC | Waterbury | Connecticut | 06708 | — |
| ALL Medical Research, LLC | Cooper City | Florida | 33024 | — |
| Advanced Pharma Research | Cutler Bay | Florida | 33189 | — |
| South Florida Wellness & Clinical Research Institute | Margate | Florida | 33063 | — |
| Suncoast Research Group, LLC | Miami | Florida | 33135 | — |
| New Horizon Research Center | Miami | Florida | 33165 | — |
| Clinical Neuroscience Solutions Inc | Orlando | Florida | 32801 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| Primary Care Specialists, LLC | Atlanta | Georgia | 30312 | — |
| Rocky Mountain Diabetes and Osteoporosis Center | Idaho Falls | Idaho | 83404 | — |
| Solaris Clinical Research | Meridian | Idaho | 83646 | — |
| Saltzer Medical Group. P.A. | Nampa | Idaho | 83686 | — |
| Northwestern Feinberg School of Medicine | Chicago | Illinois | 60611 | — |
| NorthShore University HealthSystem | Skokie | Illinois | 60077 | — |
| University of Iowa Hospital & Clinic | Iowa City | Iowa | 52242 | — |
| Iowa Diabetes Research | West Des Moines | Iowa | 50265 | — |
| Cotton O'Neil Diabetes and Endocrinology Center | Topeka | Kansas | 66606 | — |
| Robley Rex VAMC | Louisville | Kentucky | 40206 | — |
| NECCR PrimaCare Research, LLC | Fall River | Massachusetts | 02721 | — |
| AA Medical Research Center | Flint | Michigan | 48504 | — |
| Troy Internal Medicine, PC | Troy | Michigan | 48098 | — |
| Clinical Research Professionals | Chesterfield | Missouri | 63005 | — |
| Glacier View Research Institute | Kalispell | Montana | 59901 | — |
| Montana Medical Research, Inc | Missoula | Montana | 59808 | — |
| Palm Research Center | Las Vegas | Nevada | 89128 | — |
| Palm Research Center | Las Vegas | Nevada | 89148 | — |
| Southern New Hampshire Diabetes and Endocrinology | Nashua | New Hampshire | 03063 | — |
| PharmQuest | Greensboro | North Carolina | 27408 | — |
| Lillestol Research LLC | Fargo | North Dakota | 58104 | — |
| Rapid Medical Research Inc | Cleveland | Ohio | 44122 | — |
| Ohio State Univ College Of Medicine | Columbus | Ohio | 43210 | — |
| Aventiv Research | Columbus | Ohio | 43213 | — |
| Intend Research | Norman | Oklahoma | 73069 | — |
| The Corvallis Clinic P.C. | Corvallis | Oregon | 97330 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Heritage Valley Medical Group, Inc. | Beaver | Pennsylvania | 15009 | — |
| Capital Area Research | Camp Hill | Pennsylvania | 17011 | — |
| Detweiler Family Medicine | Lansdale | Pennsylvania | 19446 | — |
| Capital Area Research | Newport | Pennsylvania | 17074 | — |
| Parkside Family Medical | Philadelphia | Pennsylvania | 19144 | — |
| Preferred Primary Care Physicians- Bower Hill | Pittsburgh | Pennsylvania | 15243 | — |
| Mountain View Clinical Research, Inc. | Greer | South Carolina | 29651 | — |
| The Research Center of the Upstate | Mauldin | South Carolina | 29662 | — |
| Holston Medical Group Clinical Research | Kingsport | Tennessee | 37660 | — |
| New Phase Research & Development | Knoxville | Tennessee | 37909 | — |
| Dallas Diabetes Endocrine Center | Dallas | Texas | 75230 | — |
| PCP for Life | Houston | Texas | 77070 | — |
| BFHC Research | San Antonio | Texas | 78249 | — |
| Consano Clinical Research | Shavano Park | Texas | 78231 | — |
| Martin Diagnostic Clinic | Tomball | Texas | 77375 | — |
| Alpine Research Organization | Farmington | Utah | 84025 | — |
| Burke Internal Medicine & Research | Burke | Virginia | 22015 | — |
| Private: Dr. Larry Stonesifer | Federal Way | Washington | 98003 | — |
| Capital Clinical Research Center | Olympia | Washington | 98502 | — |
| Walla Walla Clinic | Walla Walla | Washington | 99362 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 142 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03730662, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 13, 2022 · Synced May 13, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03730662 live on ClinicalTrials.gov.