A Study of Zanubrutinib (BGB-3111) Versus Ibrutinib in Participants With Relapsed/Refractory Chronic Lymphocytic Leukemia
Public ClinicalTrials.gov record NCT03734016. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized Study of Zanubrutinib (BGB-3111) Compared With Ibrutinib in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is designed to compare the overall response rate of zanubrutinib versus ibrutinib in participants with relapsed/refractory chronic lymphocytic leukemia or small lymphocytic lymphoma.
Study identification
- NCT ID
- NCT03734016
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 652 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 1, 2018 (Actual)
- Primary completion
- Aug 8, 2022 (Actual)
- Completion
- Feb 28, 2024 (Actual)
- Last update posted
- Mar 30, 2025
2018 – 2024
United States locations
- U.S. sites
- 30
- U.S. states
- 19
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Carti Cancer Center | Little Rock | Arkansas | 72205 | — |
| David Geffen School of Medicine At UCLA | Los Angeles | California | 90095 | — |
| Rocky Mountain Cancer Centers Boulder | Boulder | Colorado | 80303 | — |
| Scri Florida Cancer Specialists South | Fort Myers | Florida | 33901 | — |
| Scri Florida Cancer Specialists North | St. Petersburg | Florida | 33705 | — |
| Augusta University | Augusta | Georgia | 30912 | — |
| Norton Cancer Institute Pavilion | Louisville | Kentucky | 40207 | — |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| Forrest General Hospital Cancer Center | Hattiesburg | Mississippi | 39401 | — |
| Scri Hca Midwest Health | Kansas City | Missouri | 64132 | — |
| Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89169 | — |
| Atlantic Health System | Morristown | New Jersey | 07960 | — |
| Morristown Medical Center | Morristown | New Jersey | 07960 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Clinical Research Alliance, Inc | Westbury | New York | 11590 | — |
| Duke University Hospital | Durham | North Carolina | 27705 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Willamette Valley Cancer Center | Springfield | Oregon | 97477 | — |
| Scri Tennessee Oncology Chattanooga | Chattanooga | Tennessee | 37404 | — |
| Sarah Cannon Cancer Center | Nashville | Tennessee | 37203 | — |
| Texas Oncology Fort Worth Cancer Center | Fort Worth | Texas | 76104-2150 | — |
| The University of Texas Md Anderson Cancer Center | Houston | Texas | 77030-4009 | — |
| Joe Arrington Cancer Research and Treatment Center | Lubbock | Texas | 79410 | — |
| Texas Oncology San Antonio Medical Center Usor | San Antonio | Texas | 78240 | — |
| Texas Oncology Tyler Longview | Tyler | Texas | 75702 | — |
| Blue Ridge Cancer Care (Oncology and Hematology Associates of Southwest Virginia) | Roanoke | Virginia | 24014 | — |
| Va Puget Sound Health Care System | Seattle | Washington | 98108 | — |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | — |
| Medical Oncology Associates | Spokane | Washington | 99208 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 85 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03734016, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 30, 2025 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03734016 live on ClinicalTrials.gov.