Optimal Post Tpa-Iv Monitoring in Ischemic Stroke
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This page only displays public information reproduced from the official ClinicalTrials.gov record NCT03734640. It adds no medical advice, opinions, or eligibility judgments. The official record remains the source of truth for eligibility criteria, enrollment, and contact information.
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Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
OPTIMISTmain is an investigator-initiated and conducted, international, multicentre, stepped wedge cluster randomized controlled trial comparing the effects of different intensities of nursing care monitoring for patients with acute ischemic stroke of mild severity and without critical care needs after IV-tPA.
Study identification
- NCT ID
- NCT03734640
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 4,922 participants
Conditions and interventions
Interventions
Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 28, 2021 (Actual)
- Primary completion
- Dec 1, 2024 (Actual)
- Completion
- Jan 23, 2025 (Actual)
- Last update posted
- Mar 26, 2025
2021 – 2025
United States locations
- U.S. sites
- 20
- U.S. states
- 13
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Centura St. Anthony Hospital | Lakewood | Colorado | 80228 | — |
| Centura Littleton Adventist Hospital | Littleton | Colorado | 80122 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| The John Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| Howard County General Hospital | Columbia | Maryland | 21044 | — |
| University of Massachusetts Worcester | Worcester | Massachusetts | 01601 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Ascension Providence Hospital | Novi | Michigan | 48374 | — |
| SSM Health DePaul Hospital | Bridgeton | Missouri | 63044 | — |
| Saint Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | — |
| Research Medical Center | Kansas City | Missouri | 64132 | — |
| Renown Health | Reno | Nevada | 89502 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Cone Health | Greensboro | North Carolina | 27401 | — |
| OhioHealth Research Institute - Riverside Methodist Hospital | Columbus | Ohio | 43214 | — |
| INTEGRIS Southwest Medical Center | Oklahoma City | Oklahoma | 73109 | — |
| Lehigh Valley Health Network | Allentown | Pennsylvania | 18103 | — |
| Penn State Health | Hershey | Pennsylvania | 17033 | — |
| Inova Fairfax Hospital | Falls Church | Virginia | 22042 | — |
| ThedaCare Regional Medical Center Appleton | Appleton | Wisconsin | 54911 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 34 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03734640, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 26, 2025 · Synced Nov 15, 2026
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