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Completed Phase 2 Interventional Results available

A Study to Assess the Safety and Efficacy of Elezanumab When Added to Standard of Care in Progressive Forms of Multiple Sclerosis

ClinicalTrials.gov ID: NCT03737812

Public ClinicalTrials.gov record NCT03737812. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 25, 2026, 11:49 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled, Multiple Dose Study to Assess the Safety and Efficacy of Elezanumab When Added to Standard of Care in Progressive Forms of Multiple Sclerosis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the safety and efficacy of elezanumab in participants with progressive Multiple Sclerosis (PMS).

Study identification

NCT ID
NCT03737812
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
AbbVie
Industry
Enrollment
123 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 27, 2019 (Actual)
Primary completion
Jan 15, 2021 (Actual)
Completion
Aug 30, 2021 (Actual)
Last update posted
Dec 21, 2023

2019 – 2021

United States locations

U.S. sites
30
U.S. states
17
U.S. cities
27
Facility City State ZIP Site status
St. Josephs Hospital and Med Center /ID# 202809 Phoenix Arizona 85013 —
Sutter East Bay Medical Foundation-Jordon Research and Education Dev. Inst. /ID# 202448 Berkeley California 94705-2017 —
The Research Center of Southern California /ID# 202802 Carlsbad California 92011-4213 —
Vladimir Royter MD /ID# 202483 Hanford California 93230-5787 —
Stanford MS Center /ID# 202445 Palo Alto California 94304-1416 —
UC Davis Health-Neurological Surgery /ID# 202485 Sacramento California 95817-2307 —
UCSF School of Medicine - Neurology /ID# 203194 San Francisco California 94143-0003 —
University of Colorado School of Medicine, Dept of Neurology /ID# 202807 Aurora Colorado 80045-2527 —
Advanced Neurosciences Research, LLC /ID# 203072 Fort Collins Colorado 80528 —
Rowe Neurology Institute /ID# 202744 Lenexa Kansas 66214 —
Duplicate_Parexel International /ID# 202747 Baltimore Maryland 21225 —
International Neurorehabilitation Institute /ID# 213333 Lutherville Maryland 21093-6016 —
Michigan Institute for Neurological Disorders (MIND) /ID# 202470 Farmington Hills Michigan 48334 —
Memorial Neurological Institute and Center for Multiple Sclerosis /ID# 206327 Owosso Michigan 48867-2116 —
Ridgeview Specialty Clinic Chaska - Neurology /ID# 204384 Chaska Minnesota 55318-4551 —
Washington University-School of Medicine /ID# 202899 St Louis Missouri 63110 —
The MS Center for Innovations in Care at Missouri Baptist Medical Center /ID# 205432 St Louis Missouri 63131-2322 —
Cleveland Clinic Lou Ruvo Cent /ID# 204744 Las Vegas Nevada 89106-0100 —
Oklahoma Med Res. Foundation /ID# 203442 Oklahoma City Oklahoma 73104 —
Providence Neurological Specialties - West /ID# 203193 Portland Oregon 97225-6646 —
Advanced Neurosciences Institute /ID# 204555 Franklin Tennessee 37064 —
KCA Neurology - Franklin /ID# 202912 Franklin Tennessee 37067-5914 —
Neurology Consultants of Dallas - LBJ Fwy /ID# 203102 Dallas Texas 75243-1188 —
Central Texas Neurology Consul /ID# 203108 Round Rock Texas 78681 —
Integrated Neurology Services /ID# 202743 Alexandria Virginia 22310 —
Evergreen Neuroscience Institute /ID# 204205 Kirkland Washington 98034-3029 —
Virginia Mason Medical Center /ID# 205439 Seattle Washington 98101 —
Swedish MS Center /ID# 202904 Seattle Washington 98122-5698 —
West Virginia Univ School Med /ID# 202849 Morgantown West Virginia 26506 —
Froedtert Memorial Lutheran Hospital /ID# 202618 Milwaukee Wisconsin 53226-3522 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03737812, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 21, 2023 · Synced Oct 25, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03737812 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →