Efficacy, Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy (ADT) in Patients With Major Depressive Disorder (MDD) Who Have Had an Inadequate Response to Antidepressants Alone
Public ClinicalTrials.gov record NCT03738215. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-Blind, Placebo-Controlled Study of Cariprazine as an Adjunct to Antidepressants in the Treatment of Patients With Major Depressive Disorder Who Have Had an Inadequate Response to Antidepressants Alone
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this study is to evaluate the efficacy, safety and tolerability of cariprazine as an adjunctive treatment to antidepressant therapy (ADT) in patients with MDD who have had an inadequate response to antidepressants alone.
Study identification
- NCT ID
- NCT03738215
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 759 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 9, 2018 (Actual)
- Primary completion
- Sep 30, 2021 (Actual)
- Completion
- Sep 30, 2021 (Actual)
- Last update posted
- Oct 25, 2022
2018 – 2021
United States locations
- U.S. sites
- 65
- U.S. states
- 25
- U.S. cities
- 62
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alea Research /ID# 234789 | Phoenix | Arizona | 85012-2707 | — |
| Atria Clinical Research /ID# 237988 | Little Rock | Arkansas | 72209-7040 | — |
| Woodland Research Northwest, LLC /ID# 236641 | Rogers | Arkansas | 72758-6442 | — |
| California Pharmaceutical Research Institute /ID# 236732 | Anaheim | California | 92804-3738 | — |
| Advanced Research Center /ID# 237957 | Anaheim | California | 92805 | — |
| Axiom Research /ID# 236268 | Colton | California | 92324 | — |
| ATP Clinical Research, Inc /ID# 236619 | Costa Mesa | California | 92626-4607 | — |
| ProScience Research Group /ID# 236442 | Culver City | California | 90230-6632 | — |
| Collaborative Neuroscience Research - Orange County /ID# 237639 | Garden Grove | California | 92845 | — |
| Irvine Clinical Research /ID# 237409 | Irvine | California | 92614 | — |
| Omega Clinical Trials LLC /ID# 238168 | La Habra | California | 90631-3842 | — |
| Synergy San Diego /ID# 236654 | Lemon Grove | California | 91945-2956 | — |
| Anderson Clinical Research /ID# 236627 | Redlands | California | 92374-4555 | — |
| Sharp Mesa Vista Hospital /ID# 235797 | San Diego | California | 92123 | — |
| Viking Clinical Research /ID# 236614 | Temecula | California | 92591-6200 | — |
| Olympian Clinical Research /ID# 237417 | Clearwater | Florida | 33756 | — |
| MD Clinical | Hallandale | Florida | 33009 | — |
| Reliable Clinical Research /ID# 234786 | Hialeah | Florida | 33012-5830 | — |
| CNS Healthcare - Jacksonville /ID# 238241 | Jacksonville | Florida | 32256-6039 | — |
| Space Coast Neuropsychiatric Research Institute /ID# 235765 | Palm Bay | Florida | 32905 | — |
| University of South Florida /ID# 234386 | Tampa | Florida | 33606 | — |
| Institute for Advanced Medical Research /ID# 236672 | Alpharetta | Georgia | 30022-1142 | — |
| iResearch Atlanta, LLC /ID# 237389 | Decatur | Georgia | 30030 | — |
| Psych Atlanta /ID# 235835 | Marietta | Georgia | 30060 | — |
| Capstone Clinical Research /ID# 236546 | Libertyville | Illinois | 60048-5341 | — |
| Pillar Clinical Research /ID# 235702 | Lincolnwood | Illinois | 60712 | — |
| NeuroPsychiatric Research Practice & Associate LTD /ID# 234636 | Winfield | Illinois | 60190 | — |
| Lake Charles Clinical Trials /ID# 237723 | Lake Charles | Louisiana | 70629 | — |
| J. Gary Booker MD APMC /ID# 234514 | Shreveport | Louisiana | 71104 | — |
| Pharmasite Research, Inc. /ID# 237395 | Baltimore | Maryland | 21208 | — |
| CBH Health LLC /ID# 234536 | Gaithersburg | Maryland | 20877 | — |
| Michigan Clinical Research Institute /ID# 234792 | Ann Arbor | Michigan | 48105-3205 | — |
| NeuroBehavioral Medicine Group /ID# 236671 | Bloomfield Hills | Michigan | 48302 | — |
| Precise Research Centers /ID# 236598 | Flowood | Mississippi | 39232-8839 | — |
| Millennium Psychiatric Associates LLC /ID# 235989 | St Louis | Missouri | 63132 | — |
| Alivation Research /ID# 236583 | Lincoln | Nebraska | 68526-9474 | — |
| Altea Research Institute /ID# 236726 | Las Vegas | Nevada | 89102-1955 | — |
| Hassman Research Institute /ID# 237501 | Berlin | New Jersey | 08009 | — |
| Integrative Clinical Trials /ID# 236656 | Brooklyn | New York | 11229-3576 | — |
| Manhattan Behavioral Medicine PLLC /ID# 236314 | New York | New York | 10036 | — |
| Finger Lakes Clinical Research /ID# 236578 | Rochester | New York | 14618-1609 | — |
| New Hope Clinical Research Inc. /ID# 234557 | Charlotte | North Carolina | 28211 | — |
| Richard Weisler MD, PA & Assoc /ID# 237424 | Raleigh | North Carolina | 27609 | — |
| Quest Therapeutics of Avon Lake /ID# 236282 | Avon Lake | Ohio | 44012 | — |
| CTI Clinical Trial and Consulting /ID# 236271 | Cincinnati | Ohio | 45212 | — |
| The Ohio State University Department of Psychiatry /ID# 234583 | Columbus | Ohio | 43210 | — |
| CincyScience /ID# 236391 | West Chester | Ohio | 45069 | — |
| IPS Research Company /ID# 237671 | Oklahoma City | Oklahoma | 73106 | — |
| Sooner Clinical Research /ID# 236346 | Oklahoma City | Oklahoma | 73112 | — |
| Oregon Center for Clinical Investigations, Inc. - Portland /ID# 236649 | Portland | Oregon | 97214-2569 | — |
| Lehigh Center for Clinical Research /ID# 236702 | Allentown | Pennsylvania | 18104-5034 | — |
| Coastal Carolina Research Center /ID# 235909 | North Charleston | South Carolina | 29405 | — |
| Psychiatric Consultants PC /ID# 235839 | Franklin | Tennessee | 37067 | — |
| Clinical Neuroscience Solutions - Memphis /ID# 237476 | Memphis | Tennessee | 38119 | — |
| Austin Clinical Trial Partners /ID# 236551 | Austin | Texas | 78737 | — |
| BioBehavioral Research of Austin /ID# 236477 | Austin | Texas | 78759-5290 | — |
| Houston Clinical Trials /ID# 234442 | Bellaire | Texas | 77401-2928 | — |
| FutureSearch Trials of Dallas, LP /ID# 236275 | Dallas | Texas | 75231 | — |
| Earle Research /ID# 236661 | Friendswood | Texas | 77546 | — |
| Red Oak Psychiatry Associates /ID# 236600 | Houston | Texas | 77090-2641 | — |
| AIM Trials /ID# 236369 | Plano | Texas | 75093 | — |
| Pillar Clinical Research LLC /ID# 234465 | Richardson | Texas | 75080 | — |
| Neuropsychiatric Associates LLC/DBA Woodstock Research Center /ID# 236087 | Woodstock | Vermont | 05091 | — |
| Northwest Clinical Research Center /ID# 237584 | Bellevue | Washington | 98007 | — |
| Core Clinical Research /ID# 236405 | Everett | Washington | 98201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 60 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03738215, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 25, 2022 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03738215 live on ClinicalTrials.gov.