Efficacy of a Plant-derived Quadrivalent Virus-like Particle (VLP) Vaccine in the Elderly
Public ClinicalTrials.gov record NCT03739112. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Observer-blind, Active Comparator-controlled, Multicenter, Phase 3 Study to Assess the Efficacy, Safety, and Immunogenicity of a Plant-derived Quadrivalent VLP Influenza Vaccine in Adults 65 Years of Age and Older
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This Phase 3 study was intended to assess the relative efficacy of the Quadrivalent VLP Influenza Vaccine during the 2018-2019 influenza season compared to a licensed vaccine in elderly adults 65 years of age and older. One dose of VLP Influenza Vaccine (30 μg/strain) or of Comparator (15 μg/strain) was to be administered to 12,738 participants.
Study identification
- NCT ID
- NCT03739112
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 12,794 participants
Conditions and interventions
Conditions
Interventions
- Quadrivalent VLP Vaccine Biological
- Fluarix Quadrivalent® Comparator Vaccine Biological
Biological
Eligibility (public fields only)
- Age range
- 65 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 17, 2018
- Primary completion
- May 16, 2019
- Completion
- Jul 15, 2019
- Last update posted
- Jun 22, 2023
2018 – 2019
United States locations
- U.S. sites
- 50
- U.S. states
- 22
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| (Site 225) Coastal Clinical Research | Mobile | Alabama | 36608 | — |
| (Site 201) Clinical Research Consortium | Tempe | Arizona | 85003 | — |
| (Site 213) Advanced Clinical Research | Banning | California | 92220 | — |
| (Site 246) Paradigm Clinical Research / Pharmaseek | Redding | California | 96001 | — |
| (Site 212) Benckmark Research | Sacramento | California | 95864 | — |
| (Site 244) Paradigm Clinical Research Center Inc | San Diego | California | 92117 | — |
| (Site 242) Paradigm Clinical Research Centers Inc | Wheat Ridge | Colorado | 80033 | — |
| (Site 239) Alliance for Multispeciality Research | Coral Gables | Florida | 33134 | — |
| (Site 222) Research Centers of America | Hollywood | Florida | 33024 | — |
| (Site 221) St-Johns Center for Clinical Research | Ponte Vedra | Florida | 32081 | — |
| (Site 231) QPS-MRA LLC | South Miami | Florida | 33143 | — |
| (Site 251) Meridian Clinical Research | Richmond Hill | Georgia | 31324 | — |
| (Site 240) Meridian Clinical Research LLC | Savannah | Georgia | 31406 | — |
| (Site 223) Clinical Research Atlanta | Stockbridge | Georgia | 30281 | — |
| (Site 249) Advanced Clinical Research | Meridian | Idaho | 83642 | — |
| (Site 219) Heartland Research Associates LLC | Augusta | Kansas | 67010 | — |
| (Site 234) Heartland Research Associates LLC | Newton | Kansas | 67114 | — |
| (Site 215) Heartland Research Associates LLC | Wichita | Kansas | 67205 | — |
| (Site 235) Heartland Research Associates LLC | Wichita | Kansas | 67207 | — |
| (Site 241) Central Kentucky Reserach Associates | Lexington | Kentucky | 40509 | — |
| (Site 203) Benchmark Research | Metairie | Louisiana | 70006 | — |
| (Site 227) Sundande Clinical Research | St Louis | Missouri | 63141 | — |
| (Site 226) Meridian Clinical Research LLC | Norfolk | Nebraska | 68701 | — |
| (Site 211) Meridian Clinical Research | Omaha | Nebraska | 68134 | — |
| (Site 209) United Medical Associates | Binghamton | New York | 13901 | — |
| (Site 217) Regional Clinical Research inc | Endwell | New York | 13760 | — |
| (Site 237) PMG Research of Cary LLC | Cary | North Carolina | 27518 | — |
| (Site 230) PMG Research of Charlotte LLC | Charlotte | North Carolina | 28209 | — |
| (Site 205) PMG Research of Rocky Mount LLC | Rocky Mount | North Carolina | 27804 | — |
| (Site 236) PMG Research | Statesville | North Carolina | 28625 | — |
| (Site 228) Research of Winston-Salem | Winston-Salem | North Carolina | 27103 | — |
| (Site 233) Sterling Research Group | Cincinnati | Ohio | 45219 | — |
| (Site 208) Sterling Research Group | Cincinnati | Ohio | 45246 | — |
| (Site 245) Rapid Medical Research | Cleveland | Ohio | 44122 | — |
| (Site 202) Aventiv Research Inc | Columbus | Ohio | 43213 | — |
| (Site 207) Lynn Institute of Norman | Norman | Oklahoma | 73069 | — |
| (Site 238) Tekton Research | Oklahoma City | Oklahoma | 73114 | — |
| (Site 216) PMG Research of Charleston LLC | Mt. Pleasant | South Carolina | 29464 | — |
| (Site 248) Coastal Carolina Research Center | Mt. Pleasant | South Carolina | 29464 | — |
| (Site 201) Meridian Clinical Research | Dakota Dunes | South Dakota | 57049 | — |
| (Site 247) New orleans Center for Clinical Research | Knoxville | Tennessee | 37920 | — |
| (Site 206) Benchmark Research | Austin | Texas | 78705 | — |
| (Site 218) Tekton Research Inc | Austin | Texas | 78745 | — |
| (Site 214) Ventavia Research Group LLC | Fort Worth | Texas | 76104 | — |
| (Site 224) Benchmark Research | Fort Worth | Texas | 76135 | — |
| (Site 232) Benchmark Research | San Angelo | Texas | 76904 | — |
| (Site 250) Clinical Trials of Texas Inc | San Antonio | Texas | 78229 | — |
| (Site 204) Jean Brown Research | Salt Lake City | Utah | 84124 | — |
| (Site 220) Advanced Clinical Research | West Jordan | Utah | 84088 | — |
| (Site 229) Clinical Research Associates of Tidewater | Norfolk | Virginia | 23507 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 54 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03739112, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 22, 2023 · Synced Sep 4, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03739112 live on ClinicalTrials.gov.