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Completed Phase 3 Interventional Results available

The Objective of This Study is to Evaluate the Efficacy, Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy (ADT) in Patients With Major Depressive Disorder (MDD) Who Have Had an Inadequate Response to Antidepressants Alone

ClinicalTrials.gov ID: NCT03739203

Public ClinicalTrials.gov record NCT03739203. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 6, 2026, 8:07 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Double-Blind, Placebo-Controlled Study of Cariprazine as an Adjunct to Antidepressants in the Treatment of Patients With Major Depressive Disorder Who Have Had an Inadequate Response to Antidepressants Alone

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The objective of this study is to evaluate the efficacy, safety and tolerability of cariprazine as an adjunctive treatment to antidepressant therapy (ADT) in patients with MDD who have had an inadequate response to antidepressants alone.

Study identification

NCT ID
NCT03739203
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
AbbVie
Industry
Enrollment
752 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 9, 2018
Primary completion
Sep 5, 2021
Completion
Sep 5, 2021
Last update posted
Sep 20, 2022

2018 – 2021

United States locations

U.S. sites
58
U.S. states
21
U.S. cities
53
Facility City State ZIP Site status
Harmonex /ID# 236936 Dothan Alabama 36303
Woodland International Research Group /ID# 236349 Little Rock Arkansas 72211
California Pharmaceutical Research Institute /ID# 236731 Anaheim California 92804-3738
Axiom Research /ID# 236267 Colton California 92324
Global Clinical Trials /ID# 235059 Costa Mesa California 92627
Collaborative Neuroscience Research - Orange County /ID# 237637 Garden Grove California 92845
Behavioral Research Specialists, LLC /ID# 236622 Glendale California 91206-4261
Sun Valley Research Center /ID# 236560 Imperial California 92251-9401
North County Clinical Research /ID# 235014 Oceanside California 92054
Excell Research, Inc /ID# 237717 Oceanside California 92056
NRC Research Institute /ID# 234632 Orange California 92868
Anderson Clinical Research /ID# 236624 Redlands California 92374-4555
Syrentis Clinical Research /ID# 237408 Santa Ana California 92705
California Neuroscience Research Medical Group, Inc. /ID# 236636 Sherman Oaks California 91403-2109
Schuster Medical Research Institute /ID# 236445 Sherman Oaks California 91403
Pacific Clinical Research Management Group /ID# 234378 Upland California 91786-3676
MCB Clinical Research Centers /ID# 236927 Colorado Springs Colorado 80910
CT Clinical Research /ID# 234638 Cromwell Connecticut 06416
Innovative Clinical Research /ID# 235186 Fort Lauderdale Florida 33319
Gulfcoast Clinical Research Center /ID# 236280 Fort Myers Florida 33912
Innova Clinical Trials /ID# 237376 Miami Florida 33133
International Research Associates, LLC /ID# 237410 Miami Florida 33183
Medical Research Group of Central Florida /ID# 237326 Orange City Florida 32763
Clinical Neuroscience Solutions, Inc /ID# 236604 Orlando Florida 32801-2986
Space Coast Neuropsychiatric Research Institute /ID# 235766 Palm Bay Florida 32905
Atlanta Center for Medical Research /ID# 234696 Atlanta Georgia 30331
Institute for Advanced Medical Research /ID# 234992 Atlanta Georgia 30341
iResearch Savannah /ID# 236082 Savannah Georgia 31405
Iris Research Inc. /ID# 234995 Smyrna Georgia 30082-2629
AMR Conventions Research /ID# 236262 Naperville Illinois 60563
Collective Medical Research /ID# 236397 Prairie Village Kansas 66208
Boston Clinical Trials /ID# 236558 Boston Massachusetts 02131-2515
BTC of New Bedford /ID# 236381 New Bedford Massachusetts 02740
The Coastal Research Associates Inc /ID# 235056 South Weymouth Massachusetts 02190
Sisu at Renaissance Medical Group /ID# 236198 Springfield Massachusetts 01103
Center for Emotional Fitness /ID# 236630 Cherry Hill New Jersey 08002-3008
Bio Behavioral Health, Inc /ID# 238209 Toms River New Jersey 08755-6434
SPRI Clinical Trails /ID# 236657 Brooklyn New York 11235-5660
Bioscience Research /ID# 234961 Mount Kisco New York 10549-3028
Fieve Clinical Research, Inc. /ID# 236632 New York New York 10017-1921
Eastside Comprehensive Medical Center LLC /ID# 236094 New York New York 10128
Clinical Trials America /ID# 237636 Hickory North Carolina 28601
Quest Therapeutics of Avon Lake /ID# 236281 Avon Lake Ohio 44012
Patient Priority Clinical Sites, LLC /ID# 236743 Cincinnati Ohio 45215-2123
North Star Medical Research LL /ID# 235076 Middleburg Heights Ohio 44130
CincyScience /ID# 236387 West Chester Ohio 45069
Lynn Health Science Institute (LHSI) /ID# 237612 Oklahoma City Oklahoma 73112
Central States Research /ID# 238295 Tulsa Oklahoma 74136
Oregon Ctr for Clin Inv /ID# 237463 Salem Oregon 97301
Keystone Clinical Studies LLC /ID# 238153 Plymouth Meeting Pennsylvania 19462
Psychiatric Consultants PC /ID# 235838 Franklin Tennessee 37067
Research Strategies of Memphis /ID# 236629 Memphis Tennessee 38119-5202
Earle Research /ID# 236660 Friendswood Texas 77546
AIM Trials /ID# 236366 Plano Texas 75093
Clinical Trials of Texas, Inc /ID# 237864 San Antonio Texas 78229
Family Psychiatry of The Woodlands /ID# 236423 The Woodlands Texas 77381
Woodstock Research Center /ID# 236653 Woodstock Vermont 05091-9795
SSM Health Dean Medical Group /ID# 238103 Madison Wisconsin 53715

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 54 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03739203, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 20, 2022 · Synced Sep 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03739203 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →