A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy
Public ClinicalTrials.gov record NCT03739840. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-Onset Seizures in Adult Subjects With Drug-Resistant Epilepsy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to evaluate the efficacy, safety and tolerability of the 3 selected dose regimens of padsevonil (PSL) administered concomitantly with up to 3 anti-epileptic drugs (AEDs) compared with placebo for treatment of observable focal-onset seizures in subjects with drug-resistant epilepsy.
Study identification
- NCT ID
- NCT03739840
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 232 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 6, 2019 (Actual)
- Primary completion
- Sep 28, 2020 (Actual)
- Completion
- Sep 28, 2020 (Actual)
- Last update posted
- Dec 21, 2022
2019 – 2020
United States locations
- U.S. sites
- 32
- U.S. states
- 20
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Ep0092 839 | Chandler | Arizona | 85226 | — |
| Ep0092 881 | Tucson | Arizona | 85724 | — |
| Ep0092 633 | Carlsbad | California | 92011 | — |
| Ep0092 629 | Orange | California | 92868 | — |
| Ep0092 845 | Washington D.C. | District of Columbia | 20037 | — |
| Ep0092 892 | Bradenton | Florida | 34209 | — |
| Ep0092 640 | Hialeah | Florida | 33016 | — |
| Ep0092 641 | Jacksonville | Florida | 32209 | — |
| Ep0092 823 | Orlando | Florida | 32806 | — |
| Ep0092 803 | Honolulu | Hawaii | 96817 | — |
| Ep0092 637 | Urbana | Illinois | 61801 | — |
| Ep0092 880 | Anderson | Indiana | 46011 | — |
| Ep0092 638 | Fort Wayne | Indiana | 46804 | — |
| Ep0092 630 | Ames | Iowa | 50010 | — |
| Ep0092 707 | Lexington | Kentucky | 40536 | — |
| Ep0092 822 | Baltimore | Maryland | 21287 | — |
| Ep0092 818 | Bethesda | Maryland | 20817 | — |
| Ep0092 889 | Boston | Massachusetts | 02215 | — |
| Ep0092 645 | Golden Valley | Minnesota | 55422 | — |
| Ep0092 644 | Minneapolis | Minnesota | 55416 | — |
| Ep0092 878 | Brooklyn | New York | 11203 | — |
| Ep0092 876 | New York | New York | 10075 | — |
| Ep0092 893 | Syracuse | New York | 13210 | — |
| Ep0092 895 | The Bronx | New York | 10467 | — |
| Ep0092 890 | Chapel Hill | North Carolina | 27599 | — |
| Ep0092 884 | Charlotte | North Carolina | 28204 | — |
| Ep0092 642 | Columbus | Ohio | 43210 | — |
| Ep0092 647 | Oklahoma City | Oklahoma | 73106 | — |
| Ep0092 882 | Portland | Oregon | 97225 | — |
| Ep0092 802 | Philadelphia | Pennsylvania | 19107 | — |
| Ep0092 829 | Charlottesville | Virginia | 22903 | — |
| Ep0092 639 | Renton | Washington | 98055 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 109 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03739840, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 21, 2022 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03739840 live on ClinicalTrials.gov.