Efficacy and Safety of Four Doses of Cenerimod Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus
Public ClinicalTrials.gov record NCT03742037. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group Study to Evaluate the Efficacy, Safety, and Tolerability of Cenerimod in Subjects With Moderate to Severe Systemic Lupus Erythematosus (SLE)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to assess the efficacy and safety of 4 doses of cenerimod versus placebo in adult subjects with systemic lupus erythematosus (SLE).
Study identification
- NCT ID
- NCT03742037
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 427 participants
Conditions and interventions
Conditions
Interventions
- Cenerimod 0.5 mg Drug
- Cenerimod 1 mg Drug
- Cenerimod 2 mg Drug
- Cenerimod 4 mg Drug
- Placebo Drug
- cenerimod 2 mg (ex-4 mg) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 21, 2018 (Actual)
- Primary completion
- Aug 31, 2021 (Actual)
- Completion
- Aug 25, 2022 (Actual)
- Last update posted
- Jul 29, 2026
2018 – 2022
United States locations
- U.S. sites
- 29
- U.S. states
- 14
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group | Anniston | Alabama | 36207 | — |
| University of California San Diego | La Jolla | California | 92037-0493 | — |
| Valerius Medical Group and Research Center | Los Alamitos | California | 90720-5403 | — |
| University of Colorado School of Medicine | Aurora | Colorado | 80045 | — |
| Robert W Levin MD PA | Clearwater | Florida | 33765 | — |
| Center for Rheumatology Immunology and Arthritis | Fort Lauderdale | Florida | 33309 | — |
| Life Clinical Trials | Margate | Florida | 33063 | — |
| D&H National Research Centers INC | Miami | Florida | 33155 | — |
| San Marcus Research Clinic | Miami Lakes | Florida | 33014 | — |
| Millennium Research | Ormond Beach | Florida | 32174-1139 | — |
| Integral Rheumatology & Immunology Specialists | Plantation | Florida | 33324 | — |
| Advanced Research Institute Inc Allergy & Rheumatology | St. Petersburg | Florida | 33708 | — |
| Axiom Clinical Research of Florida | Tampa | Florida | 33603 | — |
| North Georgia Rheumatology Group - Duluth | Lawrenceville | Georgia | 30046 | — |
| Institute of Arthritis Research | Idaho Falls | Idaho | 83404 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Innovative Health Research | Las Vegas | Nevada | 89128 | — |
| New York Presbyterian Columbia University Medical Center | New York | New York | 10032 | — |
| State University of New York Upstate Medical University | Syracuse | New York | 13210 | — |
| Joint Muscle Medical Care and Research Institute - Lilington Office | Charlotte | North Carolina | 28204 | — |
| DJL Clinical Research | Charlotte | North Carolina | 28210 | — |
| Paramount Medical Research and Consulting | Middleburg Heights | Ohio | 44130 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| Office of Ramesh C. Gupta, MD | Memphis | Tennessee | 38119 | — |
| Amarillo Center for Clinical Research | Amarillo | Texas | 79124 | — |
| Accurate Clinical Research | Houston | Texas | 77034 | — |
| Southwest Rheumatology Research, LLC | Mesquite | Texas | 75150 | — |
| Sun Research Institute | San Antonio | Texas | 78215 | — |
| Accurate Clinical Management | Stafford | Texas | 77477 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 119 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03742037, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 29, 2026 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03742037 live on ClinicalTrials.gov.