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Completed Phase 3 Interventional Results available

Topical Ruxolitinib Evaluation in Atopic Dermatitis Study 1 (TRuE AD1) - An Efficacy and Safety Study of Ruxolitinib Cream in Adolescents and Adults With Atopic Dermatitis

ClinicalTrials.gov ID: NCT03745638

Public ClinicalTrials.gov record NCT03745638. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 17, 2026, 7:07 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Double-Blind, Randomized, 8-Week, Vehicle-Controlled Efficacy and Safety Study of Ruxolitinib Cream Followed by a Long-Term Safety Extension Period in Adolescents and Adults With Atopic Dermatitis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to assess the efficacy and safety of twice daily ruxolitinib cream in adolescents and adults with Atopic Dermatitis (AD).

Study identification

NCT ID
NCT03745638
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Incyte Corporation
Industry
Enrollment
631 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
12 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 19, 2018
Primary completion
Dec 22, 2019
Completion
Nov 30, 2020
Last update posted
Sep 27, 2023

2018 – 2020

United States locations

U.S. sites
42
U.S. states
22
U.S. cities
38
Facility City State ZIP Site status
Cahaba Dermatology Birmingham Alabama 35244
Elite Clinical Studies Phoenix Arizona 85018
First OC Dermatology Fountain Valley California 92708
Dermatology Research Associates Los Angeles California 90045
Dermatology Specialists Inc Oceanside California 92056
Integrated Research Group Inc. Riverside California 92506
Advanced Rx Clinical Research Westminster California 92683
Clearlyderm Boca Raton - BTC - PPDS Boca Raton Florida 33433
Olympian Clinical Research Largo Florida 33770
Acevedo Clinical Research Miami Florida 33142
Well Pharma Medical Research Corporation Miami Florida 33143
AdvancedPharma CR LLC Miami Florida 33147
University of South Florida Tampa Florida 33613
ForCare Clinical Research Tampa Florida 33624
Metabolic Research Institute Inc West Palm Beach Florida 33401
Aeroallergy Research Lab Of Savannah Savannah Georgia 31406
Clinical Research Atlanta - ERN-PPDS Stockbridge Georgia 30281
Sneeze Wheeze and Itch Associates LLC Normal Illinois 61761
Dawes Fretzin Clinical Research Group LLC Indianapolis Indiana 46256
DS Research New Albany Indiana 47150
Kansas City Dermatology P.A. Overland Park Kansas 66215
Skin Sciences, PLLC Louisville Kentucky 40217
Michael W Simon MD Nicholasville Kentucky 40356
DermAssociates Rockville Maryland 20850
Henry Ford Medical Center Detroit Michigan 48202
JDR Dermatology Research Las Vegas Nevada 89148
Forest Hills Dermatology Group Forest Hills New York 11375
Sadick Dermatology New York New York 10075
Wake Research Associates, LLC Raleigh North Carolina 27612
Ohio Pediatric Research Assn Inc Huber Heights Ohio 45424
Central Sooner Research Norman Oklahoma 73071
Cyn3rgy Research - Clinedge - PPDS Gresham Oregon 97030
Clinical Research Institute Of Southern Oregon - Crisor Medford Oregon 97504
Oregon Medical Research Center PC Portland Oregon 97223
Oregon Health and Science University Portland Oregon 97239
Synexus Clinical Research Us Inc. Greer Greer South Carolina 29651
Alliance for Multispecialty Research, LLC Knoxville Tennessee 37920
Family Medicine Associates Of Texas Carrollton Texas 75010
Progressive Clinical Research PA San Antonio Texas 78213
Jordan Valley Medical Center West Jordan Utah 84088
PI Coor Clinical Research LLC Burke Virginia 22015
West End Dermatology Henrico Virginia 23233

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 37 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03745638, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 27, 2023 · Synced Sep 17, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03745638 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →