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Completed Phase 1 Interventional

ADVM-022 Intravitreal Gene Therapy for Wet AMD

ClinicalTrials.gov ID: NCT03748784

Public ClinicalTrials.gov record NCT03748784. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 26, 2026, 5:57 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open Label Phase 1 Study of ADVM-022 (AAV.7m8-aflibercept) in Neovascular (Wet) Age-Related Macular Degeneration

Study identification

NCT ID
NCT03748784
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Adverum Biotechnologies, Inc.
Industry
Enrollment
30 participants

Conditions and interventions

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 13, 2018
Primary completion
Jun 21, 2022
Completion
Jun 21, 2022
Last update posted
Aug 7, 2023

2018 – 2022

United States locations

U.S. sites
11
U.S. states
8
U.S. cities
11
Facility City State ZIP Site status
Adverum Clinical Site Bakersfield California 93309
Adverum Clinical Site Beverly Hills California 90211
Adverum Clinical Site Golden Colorado 80401
Adverum Clinical Site Deerfield Beach Florida 33064
Adverum Clinical Site Reno Nevada 89502
Adverum Clinical Site Philadelphia Pennsylvania 19107
Adverum Clinical Site West Columbia South Carolina 29169
Adverum Clinical Site Nashville Tennessee 37203
Adverum Clinical Site Abilene Texas 79606
Adverum Clinical Site Houston Texas 77030
Adverum Clinical Site The Woodlands Texas 77384

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03748784, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 7, 2023 · Synced Jun 26, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03748784 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →