An Extended Access Program for Bardoxolone Methyl in Patients With CKD (EAGLE)
Public ClinicalTrials.gov record NCT03749447. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Extended Access Program to Assess Long Term Safety of Bardoxolone Methyl in Patients With Chronic Kidney Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This extended access study will assess the long-term safety and tolerability of bardoxolone methyl in qualified patients with chronic kidney disease (CKD) who previously participated in one of the qualifying clinical studies with bardoxolone methyl. Patients will remain in the study until bardoxolone methyl is available through commercial channels or until patient withdrawal, whichever is sooner.
Study identification
- NCT ID
- NCT03749447
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 270 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 8, 2019 (Actual)
- Primary completion
- Aug 23, 2023 (Actual)
- Completion
- Aug 23, 2023 (Actual)
- Last update posted
- Jun 3, 2025
2019 – 2023
United States locations
- U.S. sites
- 61
- U.S. states
- 27
- U.S. cities
- 56
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Apogee Clinical Research | Huntsville | Alabama | 35805 | — |
| Arizona Kidney Disease and Hypertension Research Services, PLLC | Glendale | Arizona | 85306 | — |
| Centricity Research Phoenix Multispecialty | Mesa | Arizona | 85206 | — |
| California Institute Renal Research | La Mesa | California | 91942 | — |
| Academic Medical Research Institute | Los Angeles | California | 90022 | — |
| David Geffen School of Medicine at UCLA | Los Angeles | California | 90095 | — |
| Apex Research of Riverside | Riverside | California | 92505 | — |
| Rady Children's Hospital - San Diego | San Diego | California | 92123 | — |
| University of California San Francisco - Children's Renal Center | San Francisco | California | 94143 | — |
| University of California, San Francisco | San Francisco | California | 94143 | — |
| Western Nephrology | Arvada | Colorado | 80002 | — |
| University of Colorado Anschutz Medical Center | Aurora | Colorado | 80045 | — |
| Colorado Kidney Care, PC | Denver | Colorado | 80230 | — |
| South Florida Research Institute | Lauderdale Lakes | Florida | 33313 | — |
| Innovation Medical Research, Inc. | Palmetto Bay | Florida | 33157 | — |
| USF Health South Tampa Center | Tampa | Florida | 33606 | — |
| Florida Premier Research Institute, LLC | Winter Park | Florida | 32789 | — |
| Emory University School of Medicine | Atlanta | Georgia | 30322 | — |
| Boise Kidney & Hypertension, PLLC | Caldwell | Idaho | 83605 | — |
| Boise Kidney & Hypertension, PLLC | Meridian | Idaho | 83642 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Nephrology Research NorthShore University Health System | Evanston | Illinois | 60201 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66224 | — |
| Renal Associates of Baton Rouge | Baton Rouge | Louisiana | 70808 | — |
| Northwest Louisiana Nephrology | Shreveport | Louisiana | 71101 | — |
| The Johns Hopkins University | Baltimore | Maryland | 21287 | — |
| Tufts Medical Center - Division of Nephrology | Boston | Massachusetts | 02110 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Nephrology Center, PC | Kalamazoo | Michigan | 49007 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Children's Mercy Hospital and Clinics | Kansas City | Missouri | 64108 | — |
| Clinical Research Consultants, LLC | Kansas City | Missouri | 64111 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| KSOSN | Las Vegas | Nevada | 89128 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Mountain Kidney & Hypertension Associates | Asheville | North Carolina | 28801 | — |
| North Carolina Nephrology | Cary | North Carolina | 27511 | — |
| Metrolina Nephrology Associates | Charlotte | North Carolina | 28208 | — |
| Duke University Medical Center | Durham | North Carolina | 27701 | — |
| Metrolina Nephrology Associates | Gastonia | North Carolina | 28054 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Remington-Davis Clinical Research | Columbus | Ohio | 43215 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Northeast Clinical Research Center | Bethlehem | Pennsylvania | 18017 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| UPMC Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15224 | — |
| Columbia Nephrology Associates, PA | Columbia | South Carolina | 29203 | — |
| South Carolina Nephrology & Hypertension Center, Inc | Orangeburg | South Carolina | 29118 | — |
| Arlington Nephrology | Arlington | Texas | 76015 | — |
| Research Management, Inc. | Austin | Texas | 78751 | — |
| Renal Disease Research Institute | Dallas | Texas | 75204 | — |
| DaVita Med Center | Houston | Texas | 77004 | — |
| Southwest Houston Research | Houston | Texas | 77099 | — |
| Clinical Advancement Center | San Antonio | Texas | 78215 | — |
| University of Vermont Medical Center | Burlington | Vermont | 05401 | — |
| Nephrology Associates of Northern Virginia, Inc. | Fairfax | Virginia | 22033 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
| Milwaukee Nephrologists, SC | Wauwatosa | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 26 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03749447, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 3, 2025 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03749447 live on ClinicalTrials.gov.