A Study to Compare the Efficacy of Arfolitixorin Versus Leucovorin in Combination With 5 Fluorouracil, Oxaliplatin, and Bevacizumab in Patients With Advanced Colorectal Cancer
Public ClinicalTrials.gov record NCT03750786. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Multicenter, Parallel-group, Phase III Study to Compare the Efficacy of Arfolitixorin Versus Leucovorin in Combination With 5 Fluorouracil, Oxaliplatin, and Bevacizumab in Patients With Advanced Colorectal Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multicenter, randomized, parallel-group, Phase III study in at least 440 patients with advanced colorectal cancer to compare the efficacy of treatment with arfolitixorin versus Leucovorin in combination with 5-fluorouracil, oxaliplatin, and bevacizumab according to modified FOLFOX-6 until PD according to RECIST 1.1 criteria.
Study identification
- NCT ID
- NCT03750786
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 490 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 18, 2018 (Actual)
- Primary completion
- Nov 18, 2022 (Actual)
- Completion
- Nov 18, 2022 (Actual)
- Last update posted
- Oct 26, 2023
2018 – 2022
United States locations
- U.S. sites
- 18
- U.S. states
- 14
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| 840-24 - Banner Gateway Medical Center | Gilbert | Arizona | 85234 | — |
| 840-15 - University of Southern California | Los Angeles | California | 91001 | — |
| 840-01 - HOAG Memorial Hospital | Newport Beach | California | 92663 | — |
| 840-13 - UCH-MHS d/b/a Memorial Health System | Colorado Springs | Colorado | 80909 | — |
| 840-34 - Banner MD Anderson Cancer Center | Greeley | Colorado | 80631 | — |
| 840-32 - University of Miami | Miami | Florida | 33136 | — |
| 840-08 - Pinellas Hematology Oncology | St. Petersburg | Florida | 33709 | — |
| 840-30 - Joliet Oncology-Hematology Associates | Joliet | Illinois | 60435 | — |
| 840-06 - Cancer Center of Kansas | Wichita | Kansas | 67214 | — |
| 840-29 - Ashland-Bellefonte Cancer Center | Ashland | Kentucky | 41101 | — |
| 840-19 - University of Louisville Research Foundation Inc. (ULRF) | Louisville | Kentucky | 40202-1798 | — |
| 840-14 - University of Michigan Cancer Center | Ann Arbor | Michigan | 48109 | — |
| 840-04 - St. Vincent Frontier Cancer Center | Billings | Montana | 59102 | — |
| 840-12 - Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08903 | — |
| 840-22 - University of Oklahoma Stephenson Cancer Center | Oklahoma City | Oklahoma | 73104 | — |
| 840-10 - Oregon Health and Science University-Knight Cancer Institute | Portland | Oregon | 97239 | — |
| 840-27 - Charleston Hematology Oncology Associates | Charleston | South Carolina | 29414 | — |
| 840-02 - The University of Texas Health Science Center | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 76 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03750786, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 26, 2023 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03750786 live on ClinicalTrials.gov.