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Completed Phase 2 Interventional

Study of ANAVEX2-73 in Patients With Rett Syndrome

ClinicalTrials.gov ID: NCT03758924

Public ClinicalTrials.gov record NCT03758924. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 22, 2026, 7:01 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Double-Blind, Randomized, Placebo-Controlled, Dose Titration Study of ANAVEX2-73 in Patients With Rett Syndrome

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Phase 2 safety, tolerability and efficacy study is designed as a double-blind, randomized, placebo-controlled study. 7-week placebo-controlled study of ANAVEX2-73 oral solution for the treatment of patients with RTT 18 years or older. A voluntary option will be offered for all patients who meet the exposure criteria for ANAVEX2-73 to continue a 12-week open label extension.

Study identification

NCT ID
NCT03758924
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Anavex Life Sciences Corp.
Industry
Enrollment
31 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 45 Years
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2019 (Actual)
Primary completion
Oct 30, 2020 (Actual)
Completion
Oct 30, 2020 (Actual)
Last update posted
Jan 12, 2021

2019 – 2020

United States locations

U.S. sites
8
U.S. states
8
U.S. cities
8
Facility City State ZIP Site status
UAB | The University of Alabama at Birmingham Birmingham Alabama 35294 —
UC Davis University of California - Davis MIND Institute Sacramento California 95817 —
Rush University Medical Center Chicago Illinois 60612 —
Boston Children's Hospital Boston Massachusetts 02115 —
Washington University in St. Louis | Saint Louis Children's Hospital St Louis Missouri 63110 —
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229 —
Greenwood Genetic Center Greenwood South Carolina 29646 —
Baylor College of Medicine Houston Texas 77030 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03758924, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 12, 2021 · Synced Oct 22, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03758924 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →