An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease
Public ClinicalTrials.gov record NCT03759288. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 52-Week, Multicenter, Randomized, Double-blind, Placebo and Active-Controlled, Operationally Seamless Phase 2b/3, Parallel-group Study to Assess the Efficacy and Safety of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease (INTREPID Lead-In)
Study identification
- NCT ID
- NCT03759288
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Lead sponsor
- AstraZeneca
- Industry
- Enrollment
- 89 participants
Conditions and interventions
Conditions
Interventions
- Brazikumab low dose Drug
- Brazikumab high dose Drug
- Humira® Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 6, 2018
- Primary completion
- Oct 17, 2023
- Completion
- Oct 17, 2023
- Last update posted
- Jun 22, 2026
2018 – 2023
United States locations
- U.S. sites
- 38
- U.S. states
- 18
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Phoenix | Arizona | 85037 | — |
| Research Site | Little Rock | Arkansas | 72212 | — |
| Research Site | Lancaster | California | 93534 | — |
| Research Site | Lincoln | California | 95648 | — |
| Research Site | Poway | California | 92064 | — |
| Research Site | San Diego | California | 92103 | — |
| Research Site | Colorado Springs | Colorado | 80907 | — |
| Research Site | Boca Raton | Florida | 33487 | — |
| Research Site | Clearwater | Florida | 33756 | — |
| Research Site | Kissimmee | Florida | 34741 | — |
| Research Site | Lakeland | Florida | 33813 | — |
| Research Site | Miami | Florida | 33157 | — |
| Research Site | Miami | Florida | 33165 | — |
| Research Site | Miami | Florida | 33189 | — |
| Research Site | Miami Lakes | Florida | 33016 | — |
| Research Site | Naples | Florida | 34102 | — |
| Research Site | St. Petersburg | Florida | 33710 | — |
| Research Site | Tampa | Florida | 33626 | — |
| Research Site | Atlanta | Georgia | 30328 | — |
| Research Site | Atlanta | Georgia | 30342 | — |
| Research Site | Decatur | Georgia | 30033 | — |
| Research Site | Oak Lawn | Illinois | 60453 | — |
| Research Site | Brownsburg | Indiana | 46112 | — |
| Research Site | Chesterfield | Michigan | 48047 | — |
| Research Site | Las Vegas | Nevada | 89123 | — |
| Research Site | Albuquerque | New Mexico | 87108 | — |
| Research Site | Morehead City | North Carolina | 28557 | — |
| Research Site | Beachwood | Ohio | 44122 | — |
| Research Site | Oklahoma City | Oklahoma | 73102 | — |
| Research Site | Uniontown | Pennsylvania | 15401 | — |
| Research Site | Carrollton | Texas | 75007 | — |
| Research Site | Houston | Texas | 77017 | — |
| Research Site | Houston | Texas | 77058 | — |
| Research Site | McAllen | Texas | 78503 | — |
| Research Site | Pflugerville | Texas | 78660 | — |
| Research Site | Stafford | Texas | 77477 | — |
| Research Site | North Chesterfield | Virginia | 23236 | — |
| Research Site | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 64 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03759288, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 22, 2026 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03759288 live on ClinicalTrials.gov.