Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart Failure
Public ClinicalTrials.gov record NCT03759392. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart Failure With Reduced Ejection Fraction and Decreased Exercise Tolerance
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the effect of treatment with omecamtiv mecarbil compared with placebo on exercise capacity as determined by cardiopulmonary exercise testing following 20 weeks of treatment with omecamtiv mecarbil or placebo
Study identification
- NCT ID
- NCT03759392
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 276 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 9, 2019 (Actual)
- Primary completion
- Nov 8, 2021 (Actual)
- Completion
- Jan 6, 2022 (Actual)
- Last update posted
- Mar 7, 2023
2019 – 2022
United States locations
- U.S. sites
- 36
- U.S. states
- 24
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alaska Heart and Vascular Institute | Anchorage | Alaska | 99508 | — |
| Arkansas Cardiology Clinic | Little Rock | Arkansas | 72205 | — |
| Harbor-UCLA Medical Center | Torrance | California | 90509 | — |
| South Denver Cardiology Associates, PC | Littleton | Colorado | 80120 | — |
| Hartford Hospital-University of Connecticut School of Medicine | Hartford | Connecticut | 06102 | — |
| Holy Cross Hospital - Fort Lauderdale | Fort Lauderdale | Florida | 33308-4603 | — |
| Broward Research Center - Pembroke Pines | Pembroke Pines | Florida | 33024 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Community Hospital South, Inc. | Indianapolis | Indiana | 46227 | — |
| Saint Vincent Medical Group Inc. | Indianapolis | Indiana | 46260 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Massachusetts General Hospital (MGH) - Cardiac Unit Associates | Boston | Massachusetts | 02114-2621 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Heart & Vascular Institute | Detroit | Michigan | 48202 | — |
| McLaren Health Care Corporation | Petoskey | Michigan | 49770 | — |
| Michigan Heart | Ypsilanti | Michigan | 48197 | — |
| Saint Luke's Health System | Kansas City | Missouri | 64111 | — |
| Glacier View Research Institute, Cardiology | Kalispell | Montana | 59901 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Cardiovascular Associates Of The Delaware Valley (Cadv), P.A. - Elmer Physicians Care Center - Elmer | Elmer | New Jersey | 08318 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112 | — |
| NYU Langone Medical Center | New York | New York | 10016 | — |
| Queens Heart Institute | Rosedale | New York | 11422 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Wake Med Health and Hospital | Raleigh | North Carolina | 27610 | — |
| Wake Forest University School of Medicine | Winston-Salem | North Carolina | 27101 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| St. John Clinical Research Institute | Tulsa | Oklahoma | 74104 | — |
| Oregon Health | Portland | Oregon | 97239 | — |
| Capital Area Research, LLC | Camp Hill | Pennsylvania | 17011 | — |
| Penn State Hershey Children's Hospital | Hershey | Pennsylvania | 17033 | — |
| Lancaster Heart And Stroke Foundation | Lancaster | Pennsylvania | 17603 | — |
| Greenville Health System | Greenville | South Carolina | 29605 | — |
| University of Texas - Southwestern Medical Center | Dallas | Texas | 75235 | — |
| Baylor Scott and White Heart and Vascular Hospital | Dallas | Texas | 75246 | — |
| Inova Heart and Vascular Institute | Falls Church | Virginia | 22042 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 45 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03759392, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 7, 2023 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03759392 live on ClinicalTrials.gov.