A Study to Evaluate the Efficacy and Safety of Intrathecally Administered RO7234292 (RG6042) in Participants With Manifest Huntington's Disease
Public ClinicalTrials.gov record NCT03761849. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Multicenter, Double-Blind, Placebo-Controlled, Phase III Clinical Study to Evaluate the Efficacy and Safety of Intrathecally Administered RO7234292 (RG6042) in Patients With Manifest Huntington's Disease
Study identification
- NCT ID
- NCT03761849
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 899 participants
Conditions and interventions
Conditions
Interventions
- RO7234292 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 25 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 22, 2019
- Primary completion
- Mar 23, 2022
- Completion
- Mar 23, 2022
- Last update posted
- Feb 29, 2024
2019 – 2022
United States locations
- U.S. sites
- 20
- U.S. states
- 16
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Uab Medicine | Birmingham | Alabama | 35294 | — |
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| University of California San Diego | La Jolla | California | 92037-1337 | — |
| Stanford Univ Medical Center | Palo Alto | California | 94304 | — |
| SC3 Research Group, Inc | Pasadena | California | 91105 | — |
| University of California Davis Medical System | Sacramento | California | 95817 | — |
| CenExel Rocky Mountain Clinical Research, LLC | Englewood | Colorado | 80113 | — |
| Georgetown University; Research Division, Psychiatry | Washington D.C. | District of Columbia | 20007 | — |
| University of South Florida | Tampa | Florida | 33613 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| John Hopkins University School of Medicine | Baltimore | Maryland | 21287 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Dent Neurological Institute | Amherst | New York | 14226 | — |
| Columbia University | New York | New York | 10032-3725 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37212 | — |
| The University of Texas Health Science Center at Houston; McGovern Medical School | Houston | Texas | 77030 | — |
| University of Utah Clinical Neurosciences Center | Salt Lake City | Utah | 84132 | — |
| Evergreen Health Care Center | Kirkland | Washington | 98034 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 76 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03761849, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 29, 2024 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03761849 live on ClinicalTrials.gov.