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Terminated Phase 3 Interventional Results available

A Study to Evaluate the Safety, Tolerability, and Efficacy of SAGE-217 Compared to Placebo in Adult Participants With Comorbid Major Depressive Disorder (MDD) and Insomnia

ClinicalTrials.gov ID: NCT03771664

Public ClinicalTrials.gov record NCT03771664. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 4:33 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-controlled Study of the Safety, Tolerability, and Efficacy of SAGE-217 Compared to Placebo in Adult Subjects With Comorbid Major Depressive Disorder and Insomnia

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is a randomized, double-blind, placebo-controlled study of the safety, tolerability, and efficacy of SAGE-217 compared to placebo in adult participants with comorbid major depressive disorder (MDD) and insomnia.

Study identification

NCT ID
NCT03771664
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Biogen
Industry
Enrollment
87 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 64 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 3, 2019
Primary completion
Dec 19, 2019
Completion
Jan 16, 2020
Last update posted
Nov 28, 2023

2019 – 2020

United States locations

U.S. sites
28
U.S. states
17
U.S. cities
27
Facility City State ZIP Site status
Sage Investigational Site Little Rock Arkansas 72211
Sage Investigational Site Rogers Arkansas 72758
Sage Investigational Site Garden Grove California 92845
Sage Investigational Site Oceanside California 92056
Sage Investigational Site San Diego California 92103
Sage Investigational Site Temecula California 92591
Sage Investigational Site Fort Myers Florida 33912
Sage Investigational Site Hollywood Florida 33024
Sage Investigational Site Miami Lakes Florida 33016
Sage Investigational Site North Miami Florida 33161
Sage Investigational Site Atlanta Georgia 30331
Sage Investigational Site Atlanta Georgia 30342
Sage Investigational Site Decatur Georgia 30030
Sage Investigational Site Chicago Illinois 60634
Sage Investigational Site Lake Charles Louisiana 70629
Sage Investigational Site Flowood Mississippi 39232
Sage Investigational Site St Louis Missouri 63141
Sage Investigational Site Las Vegas Nevada 89102
Sage Investigational Site Berlin New Jersey 08009
Sage Investigational Site Albuquerque New Mexico 87109
Sage Investigational Site Brooklyn New York 11235
Sage Investigational Site New York New York 10019
Sage Investigational Site Cincinnati Ohio 45212
Sage Investigational Site Dayton Ohio 45417
Sage Investigational Site Oklahoma City Oklahoma 73103
Sage Investigational Site Salem Oregon 97301
Sage Investigational Site Charleston South Carolina 29407
Sage Investigational Site Austin Texas 78754

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03771664, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 28, 2023 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03771664 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →