Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Terminated Phase 1 Interventional

A Study of CC-95251, a Monoclonal Antibody Directed Against SIRPα, in Participants With Advanced Solid and Hematologic Cancers

ClinicalTrials.gov ID: NCT03783403

Public ClinicalTrials.gov record NCT03783403. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 9, 2026, 1:48 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1, Open-label, Dose Finding Study of CC-95251, a Monoclonal Antibody Directed Against SIRPα, Alone and in Combination With Cetuximab or Rituximab in Subjects With Advanced Solid and Hematologic Cancers

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the safety, tolerability, and preliminary clinical activity of CC-95251 as a single agent and in combination with cetuximab and rituximab in participants with advanced solid and hematologic cancers.

Study identification

NCT ID
NCT03783403
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
Celgene
Industry
Enrollment
206 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 1, 2019 (Actual)
Primary completion
Aug 5, 2024 (Actual)
Completion
Aug 5, 2024 (Actual)
Last update posted
Sep 19, 2024

2019 – 2024

United States locations

U.S. sites
13
U.S. states
12
U.S. cities
13
Facility City State ZIP Site status
Local Institution - 105 Birmingham Alabama 35294 —
Local Institution - 101 Scottsdale Arizona 85258 —
Local Institution - 112 Sacramento California 95817 —
Rocky Mountain Cancer Centers, LLP [Aurora-COAU] Aurora Colorado 80012 —
Local Institution - 115 St Louis Missouri 63110 —
Local Institution - 110 New York New York 10016 —
Local Institution - 109 Charlotte North Carolina 28204 —
Local Institution - 106 Oklahoma City Oklahoma 73104 —
Local Institution - 113 Portland Oregon 97213 —
Local Institution - 107 Pittsburgh Pennsylvania 15232 —
Local Institution - 102 Nashville Tennessee 37203-1625 —
Local Institution - 108 Houston Texas 77030 —
Local Institution - 103 San Antonio Texas 78229 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 18 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03783403, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 19, 2024 · Synced Oct 9, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03783403 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →