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Terminated Phase 3 Interventional Results available

Inhaled Treprostinil in Participants With Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease (PH-COPD)

ClinicalTrials.gov ID: NCT03794583

Public ClinicalTrials.gov record NCT03794583. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 12:47 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-Label Extension Study of Inhaled Treprostinil in Patients With Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease (PH-COPD)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This open-label study will evaluate the safety of continued therapy with inhaled treprostinil in participants who have completed Study RIN-PH-304 (NCT03496623). This study hypothesizes that long-term safety findings will be similar to those observed in the randomized, placebo-controlled, double-blind, adaptive study 'A Phase 3, Randomized, Placebo-controlled, Double-blind, Adaptive Study to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Patients with Pulmonary Hypertension due to Chronic Obstructive Pulmonary Disease (PH-COPD)(RIN-PH-304).

Study identification

NCT ID
NCT03794583
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
United Therapeutics
Industry
Enrollment
41 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 20, 2018
Primary completion
Nov 28, 2022
Completion
Nov 28, 2022
Last update posted
May 26, 2026

2018 – 2022

United States locations

U.S. sites
28
U.S. states
18
U.S. cities
26
Facility City State ZIP Site status
The University of Alabama at Birmingham Birmingham Alabama 35294
University of California Davis Medical Center Sacramento California 95817
St. Francis Sleep Allergy & Lung Institute Clearwater Florida 33765
St. Vincent's Lung, Sleep, and Criticial Care Specialists Jacksonville Florida 32204
Mayo Clinic - Jacksonville Jacksonville Florida 32224
University of Miami Hospital Miami Florida 33136
Pulmonary & Critical Care of Atlanta Atlanta Georgia 30342
Georgia Clinical Research Austell Georgia 30106
University of Illinois Medical Center Chicago Illinois 60612
St. Vincent Medical Group, Inc. Indianapolis Indiana 46260
Kentuckiana Pulmonary Associates Louisville Kentucky 40202
University of Maryland Medical Center Baltimore Maryland 21201
Brigham and Women's Hospital Boston Massachusetts 02115
Spectrum Health Grand Rapids Michigan 49546
Memorial Hospital at Gulfport Gulfport Mississippi 39501
Albany Medical Center Albany New York 12208
Mount Sinai Medical Center New York New York 10029
University of Rochester Medical Center Rochester New York 14623
University of North Carolina at Chapel Hill Chapel Hill North Carolina 27599
The Carl and Edyth Lindner Research Center at The Christ Hospital Cincinnati Ohio 45219
Cleveland Clinic Cleveland Ohio 44195
Allegheny General Hospital Pittsburgh Pennsylvania 15212
University of Pittsburgh Medical Center Pittsburgh Pennsylvania 15213
Medical University of South Carolina Charleston South Carolina 29425
Inova Fairfax Hospital Falls Church Virginia 22042
Pulmonary Associates of Richmond, Inc. Richmond Virginia 23230
Carilion Clinic Roanoke Virginia 24014
University of Wisconsin School of Medicine and Public Health Madison Wisconsin 53792

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03794583, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 26, 2026 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03794583 live on ClinicalTrials.gov.

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