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Terminated Phase 3 Interventional Results available

Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Patients With Visual Impairment Due to Macular Edema Secondary to Branch Retinal Vein Occlusion

ClinicalTrials.gov ID: NCT03802630

Public ClinicalTrials.gov record NCT03802630. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:05 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Eighteen-Month, Two-Arm, Randomized, Double Masked, Multicenter, Phase III Study Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Adult Patients With Visual Impairment Due to Macular Edema Secondary to Branch Retinal Vein Occlusion

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study was to evaluate the efficacy and safety of brolucizumab in treatment of patients with macular edema (ME) secondary to branch retinal vein occlusion (BRVO).

Study identification

NCT ID
NCT03802630
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
450 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 2, 2019 (Actual)
Primary completion
Jul 26, 2021 (Actual)
Completion
Jul 26, 2021 (Actual)
Last update posted
Jan 30, 2023

2019 – 2021

United States locations

U.S. sites
26
U.S. states
14
U.S. cities
24
Facility City State ZIP Site status
Novartis Investigative Site Phoenix Arizona 85020 —
Novartis Investigative Site Mountain View California 94040 —
Novartis Investigative Site Santa Barbara California 93103 —
Novartis Investigative Site Colorado Springs Colorado 80909 —
Novartis Investigative Site Pensacola Florida 32503 —
Novartis Investigative Site St. Petersburg Florida 33711 —
Novartis Investigative Site Indianapolis Indiana 46280 —
Novartis Investigative Site New Albany Indiana 47150 —
Novartis Investigative Site Leawood Kansas 66211 —
Novartis Investigative Site Lenexa Kansas 66215 —
Novartis Investigative Site Stoneham Massachusetts 02180 —
Novartis Investigative Site Reno Nevada 89502 —
Novartis Investigative Site Bloomfield New Jersey 07003 —
Novartis Investigative Site Asheville North Carolina 28803 —
Novartis Investigative Site Charlotte North Carolina 28210 —
Novartis Investigative Site Cleveland Ohio 44122 —
Novartis Investigative Site Monroeville Pennsylvania 15146 —
Novartis Investigative Site Abilene Texas 79606 —
Novartis Investigative Site Arlington Texas 76012 —
Novartis Investigative Site Austin Texas 78731 —
Novartis Investigative Site Austin Texas 78750 —
Novartis Investigative Site Bellaire Texas 77401 —
Novartis Investigative Site Houston Texas 77025 —
Novartis Investigative Site Houston Texas 77030 —
Novartis Investigative Site San Antonio Texas 78240 —
Novartis Investigative Site Madison Wisconsin 53705-3611 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 76 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03802630, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 30, 2023 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03802630 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →