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Terminated Phase 3 Interventional Results available

Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Patients With Visual Impairment Due to Macular Edema Secondary to Branch Retinal Vein Occlusion

ClinicalTrials.gov ID: NCT03802630

Public ClinicalTrials.gov record NCT03802630. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 2:27 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Eighteen-Month, Two-Arm, Randomized, Double Masked, Multicenter, Phase III Study Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Adult Patients With Visual Impairment Due to Macular Edema Secondary to Branch Retinal Vein Occlusion

Study identification

NCT ID
NCT03802630
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
450 participants

Conditions and interventions

Interventions

  • Brolucizumab 6 mg Drug
  • Aflibercept 2 mg Drug
  • Sham injection Other

Drug · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 1, 2019
Primary completion
Jul 25, 2021
Completion
Jul 25, 2021
Last update posted
Jan 29, 2023

2019 – 2021

United States locations

U.S. sites
26
U.S. states
14
U.S. cities
24
Facility City State ZIP Site status
Novartis Investigative Site Phoenix Arizona 85020
Novartis Investigative Site Mountain View California 94040
Novartis Investigative Site Santa Barbara California 93103
Novartis Investigative Site Colorado Springs Colorado 80909
Novartis Investigative Site Pensacola Florida 32503
Novartis Investigative Site St. Petersburg Florida 33711
Novartis Investigative Site Indianapolis Indiana 46280
Novartis Investigative Site New Albany Indiana 47150
Novartis Investigative Site Leawood Kansas 66211
Novartis Investigative Site Lenexa Kansas 66215
Novartis Investigative Site Stoneham Massachusetts 02180
Novartis Investigative Site Reno Nevada 89502
Novartis Investigative Site Bloomfield New Jersey 07003
Novartis Investigative Site Asheville North Carolina 28803
Novartis Investigative Site Charlotte North Carolina 28210
Novartis Investigative Site Cleveland Ohio 44122
Novartis Investigative Site Monroeville Pennsylvania 15146
Novartis Investigative Site Abilene Texas 79606
Novartis Investigative Site Arlington Texas 76012
Novartis Investigative Site Austin Texas 78731
Novartis Investigative Site Austin Texas 78750
Novartis Investigative Site Bellaire Texas 77401
Novartis Investigative Site Houston Texas 77025
Novartis Investigative Site Houston Texas 77030
Novartis Investigative Site San Antonio Texas 78240
Novartis Investigative Site Madison Wisconsin 53705-3611

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 76 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03802630, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 29, 2023 · Synced Jul 22, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03802630 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →