Efficacy Study of Pilocarpine HCl Ophthalmic Solution (AGN-190584) in Participants With Presbyopia
Public ClinicalTrials.gov record NCT03804268. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Double-Masked, Randomized, Vehicle-Controlled, Parallel-Group Study Evaluating the Safety and Efficacy of AGN-190584 in Participants With Presbyopia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A study to evaluate the efficacy, safety, and pharmacokinetics of pilocarpine hydrochloride (HCl) ophthalmic solution (AGN-190584) when administered bilaterally, once daily for 30 days in participants with presbyopia.
Study identification
- NCT ID
- NCT03804268
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 323 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 55 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 21, 2018 (Actual)
- Primary completion
- Oct 31, 2019 (Actual)
- Completion
- Oct 31, 2019 (Actual)
- Last update posted
- Dec 28, 2021
2018 – 2019
United States locations
- U.S. sites
- 36
- U.S. states
- 19
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Eye Center | Chandler | Arizona | 85224 | — |
| Schwartz Laser Eye Center | Scottsdale | Arizona | 85260 | — |
| Assil Eye Institute | Beverly Hills | California | 90210 | — |
| American Institute of Research | Los Angeles | California | 90017 | — |
| Eye Research Foundation | Newport Beach | California | 92663 | — |
| Martel Eye Medical Group | Rancho Cordova | California | 95670 | — |
| Grutzmacher & Lewis, A Medical Corporation DBA Sacramento Eye Consultants | Sacramento | California | 95815 | — |
| Haas Vision Center | Colorado Springs | Colorado | 80919 | — |
| Danbury Eye Physicians and Surgeons P.C. | Danbury | Connecticut | 06810 | — |
| The Eye Associates | Bradenton | Florida | 34209 | — |
| Bruce Segal, MD | Delray Beach | Florida | 33484 | — |
| Direct Helpers Research Center | Hialeah | Florida | 33012 | — |
| Research Centers of America | Hollywood | Florida | 33024 | — |
| Florida Eye Associates | Melbourne | Florida | 32901 | — |
| USF Eye Institute | Tampa | Florida | 33612 | — |
| Price Vision Group | Indianapolis | Indiana | 46260 | — |
| Sabates Eye Centers | Leawood | Kansas | 66211 | — |
| The Eye Care Institute | Louisville | Kentucky | 40206 | — |
| Seidenberg Protzko Eye Associates | Havre de Grace | Maryland | 21078 | — |
| Tauber Eye Center | Kansas City | Missouri | 64111 | — |
| Alterman, Modi & Wolter | Poughkeepsie | New York | 12603 | — |
| Rochester Ophthalmological Group, PC | Rochester | New York | 14618 | — |
| Mundorf Eye Center | Charlotte | North Carolina | 28204 | — |
| The Ohio State University | Columbus | Ohio | 43212 | — |
| EyeCare Professionals DWA Insight Research Clinic, LLC | Powell | Ohio | 43065 | — |
| Devers Eye Institute | Portland | Oregon | 97210 | — |
| Scott & Christie and Associates, PC | Cranberry Township | Pennsylvania | 16066 | — |
| Black Hills Regional Eye Institute | Rapid City | South Dakota | 57701 | — |
| Vance Thompson Vision | Sioux Falls | South Dakota | 57108 | — |
| Southern College of Optometry | Memphis | Tennessee | 38104 | — |
| Nashville Vision Associates | Nashville | Tennessee | 37205 | — |
| Hill Country Eye Center | Cedar Park | Texas | 78613 | — |
| Key-Whitman Eye Center | Dallas | Texas | 75243 | — |
| PNV Clinical Research LLC | San Antonio | Texas | 78229 | — |
| R and R Eye Research, LLC | San Antonio | Texas | 78229 | — |
| Hoopes, Durrie, Rivera Research | Draper | Utah | 84020 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03804268, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 28, 2021 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03804268 live on ClinicalTrials.gov.