Study to Evaluate the Efficacy and Safety of Vibegron Administered Orally for 12 Weeks to Women With Irritable Bowel Syndrome
Public ClinicalTrials.gov record NCT03806127. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Vibegron Administered Orally for 12 Weeks to Women With Irritable Bowel Syndrome
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the efficacy and safety of vibegron, a beta-3 adrenergic receptor (β3-AR) agonist, in the treatment of pain associated with irritable bowel syndrome (IBS) due to IBS with predominant diarrhea (IBS-D) or mixed episodes of diarrhea and constipation (IBS-M).
Study identification
- NCT ID
- NCT03806127
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 222 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 31, 2018 (Actual)
- Primary completion
- Sep 25, 2020 (Actual)
- Completion
- Oct 6, 2020 (Actual)
- Last update posted
- Aug 2, 2021
2018 – 2020
United States locations
- U.S. sites
- 41
- U.S. states
- 18
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Synexus Clinical Research US, Inc.-Simon Williamson Clinic | Birmingham | Alabama | 35211 | — |
| Clinical Research Associates | Huntsville | Alabama | 35801 | — |
| Alabama Medical Group, PC | Mobile | Alabama | 36693 | — |
| Hope Research Institute | Chandler | Arizona | 85224 | — |
| Synexus Clinical Research US, Inc. - East Valley Family Physicians, PLC | Chandler | Arizona | 85224 | — |
| Synexus Clinical Research US, Inc. - Central Arizona Medical Associates, PC | Mesa | Arizona | 85206 | — |
| Synexus Clinical Research US, Inc. - Desert Clinical Research, LLC | Mesa | Arizona | 85213 | — |
| Synexus - Clinical Research Advantage, Inc. - Central Phoenix Medical Clinic LLC | Phoenix | Arizona | 85020 | — |
| GW Research Inc - ClinEdge-PPDS | Chula Vista | California | 91910 | — |
| Triwest Research Associates, LLC | La Mesa | California | 91942 | — |
| VA Long Beach Healthcare System - NAVREF | Long Beach | California | 90822 | — |
| Southern California Research Institute Medical Group, Inc. | Los Angeles | California | 90045 | — |
| Desta Digestive Disease Medical Center | San Diego | California | 92114 | — |
| Medical Associates Research Group, Inc. | San Diego | California | 92123 | — |
| Torrance Clinical Research | Torrance | California | 90505 | — |
| Medical Research Center of Connecticut LLC | Hamden | Connecticut | 06518 | — |
| Mayo Clinic - Division of Gastroenterology | Jacksonville | Florida | 32224 | — |
| Florida Center For Gastroenterology | Largo | Florida | 33777 | — |
| Clinical Research Center of Florida | Pompano Beach | Florida | 33060 | — |
| Palm Beach Research - ClinEdge - PPDS | West Palm Beach | Florida | 33409 | — |
| RNA America, LLC | Sugar Hill | Georgia | 30518 | — |
| Investigators Research Group, LLC | Indianapolis | Indiana | 46268 | — |
| Mandeville Private Physician Group, LLC | Mandeville | Louisiana | 70471 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Clinical Research Institute of Michigan | Chesterfield | Michigan | 48047 | — |
| Synexus Clinical Research US, Inc. - Rita B. Chuang, MD, LLC | Henderson | Nevada | 89502 | — |
| Advanced Research Institute | Reno | Nevada | 89511 | — |
| Atrium Healthcare Center for Digestive Health | Charlotte | North Carolina | 28204 | — |
| Carolina Digestive Diseases | Greenville | North Carolina | 27834 | — |
| East Carolina Gastroenterology | Jacksonville | North Carolina | 28546 | — |
| Dayton Gastroenterology, Inc. | Beavercreek | Ohio | 45440 | — |
| Central Sooner Research | Norman | Oklahoma | 73071 | — |
| Synexus Clinical Research US, Inc. - Anderson | Anderson | South Carolina | 29621 | — |
| Chattanooga Medical Research Inc | Chattanooga | Tennessee | 37404 | — |
| Clinical Research Solutions PC | Jackson | Tennessee | 38305 | — |
| DHAT Research Institute | Garland | Texas | 75044 | — |
| University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| Synexus Clinical Research US, Inc.-Plano | Plano | Texas | 75093 | — |
| Synexus Clinical Research US, Inc. - Wasatch Peak Family Practice | Layton | Utah | 84041 | — |
| Advanced Research Institute | South Ogden | Utah | 84405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03806127, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 2, 2021 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03806127 live on ClinicalTrials.gov.