Study to Assess the Efficacy, Safety, and Tolerability of Vixarelimab in Reducing Pruritus in Prurigo Nodularis
Public ClinicalTrials.gov record NCT03816891. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a/b, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of KPL-716 in Reducing Pruritus in Subjects With Prurigo Nodularis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Study of the efficacy, safety, tolerability, pharmacokinetics (PK), and immunogenicity of Vixarelimab (KPL-716) in subjects with prurigo nodularis (PN).
Study identification
- NCT ID
- NCT03816891
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 240 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 11, 2019 (Actual)
- Primary completion
- Dec 28, 2022 (Actual)
- Completion
- Aug 24, 2023 (Actual)
- Last update posted
- Jan 13, 2026
2019 – 2023
United States locations
- U.S. sites
- 40
- U.S. states
- 19
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Research Center | Phoenix | Arizona | 85053 | — |
| Investigate MD, LLC | Scottsdale | Arizona | 85255 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| First OC Dermatology | Fountain Valley | California | 92708 | — |
| Center for Dermatology Clinical Research, Inc. | Fremont | California | 94538 | — |
| Dermatology Research Associates | Los Angeles | California | 90045 | — |
| Wallace Medical Group, Inc. | Los Angeles | California | 90056 | — |
| Velocity Clinical Research - North Hollywood | North Hollywood | California | 91606 | — |
| Colorado Center for Dermatology, PLLC | Centennial | Colorado | 80111 | — |
| George Washington University Medical Faculty Associates | Washington D.C. | District of Columbia | 20037 | — |
| Rybear, Inc. | Fort Lauderdale | Florida | 33316 | — |
| University of Florida, Department of Dermatology | Gainesville | Florida | 32610 | — |
| Olympian Clinical Research | Largo | Florida | 33770 | — |
| University of Miami Itch Center | Miami | Florida | 33136 | — |
| Riverchase Dermatology | Pembroke Pines | Florida | 33028 | — |
| Olympian Clinical Research | St. Petersburg | Florida | 33709 | — |
| Advanced Clinical Research Institute | Tampa | Florida | 33607 | — |
| Palm Harbor Dermatology | Tampa | Florida | 33609 | — |
| Olympian Clinical Research | Tampa | Florida | 33614 | — |
| Alliance Clinical Research of Tampa | Tampa | Florida | 33615 | — |
| Integrated Clinical Research | West Palm Beach | Florida | 33406 | — |
| Advanced Medical Research PC | Sandy Springs | Georgia | 30328 | — |
| DS Research | New Albany | Indiana | 47150 | — |
| DS Research | Louisville | Kentucky | 40241 | — |
| ALLCUTIS Research, LLC | Beverly | Massachusetts | 01915 | — |
| ActivMed Practices & Research, Inc. | Methuen | Massachusetts | 01844 | — |
| Michigan Center for Skin Care Research | Clinton Township | Michigan | 48038 | — |
| Hamzavi Dermatology | Fort Gratiot | Michigan | 48059 | — |
| Somerset Skin Centre | Troy | Michigan | 48084 | — |
| Grekin Skin Institute | Warren | Michigan | 08088 | — |
| Skin Specialists, PC | Omaha | Nebraska | 68144 | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Bobby Buka MD, PC | New York | New York | 10012 | — |
| University of Rochester Dermatology at College Town | Rochester | New York | 14620 | — |
| Wright State Physicians | Fairborn | Ohio | 45324 | — |
| Paddington Testing Co., Inc. | Philadelphia | Pennsylvania | 19103 | — |
| Medical University of South Carolina, Department of Dermatology and Dermatological Surgery | Charleston | South Carolina | 29425 | — |
| Austin Institute for Clinical Research, Inc. | Pflugerville | Texas | 78660 | — |
| Progressive Clinical Research, PA | San Antonio | Texas | 78213 | — |
| Dermatology Specialists of Spokane | Spokane | Washington | 99202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 46 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03816891, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 13, 2026 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03816891 live on ClinicalTrials.gov.