A Research Study to See How Semaglutide Works Compared to Placebo in People With Type 2 Diabetes and Chronic Kidney Disease
Public ClinicalTrials.gov record NCT03819153. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Effect of Semaglutide Versus Placebo on the Progression of Renal Impairment in Subjects With Type 2 Diabetes and Chronic Kidney Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The researchers are doing this study to see if semaglutide can slow down the growth and worsening of chronic kidney disease in people with type 2 diabetes. Participants will get semaglutide (active medicine) or placebo ('dummy medicine'). This is known as participants' study medicine - which treatment participants get is decided by chance. Semaglutide is a medicine, doctors can prescribe in some countries for the treatment of type 2 diabetes. Participants will get the study medicine in a pen. Participants will use the pen to inject the medicine in a skin fold once a week. The study will close when there is enough information collected to show clear result of the study. The total time participants will be in this study is about 3 to 5 years, but it could be longer.
Study identification
- NCT ID
- NCT03819153
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 3,533 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 17, 2019 (Actual)
- Primary completion
- Jan 9, 2024 (Actual)
- Completion
- Jan 9, 2024 (Actual)
- Last update posted
- Mar 20, 2025
2019 – 2024
United States locations
- U.S. sites
- 117
- U.S. states
- 29
- U.S. cities
- 98
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Dr. Terence Hart | Tuscumbia | Alabama | 35674 | — |
| California Inst Of Renal Res | Chula Vista | California | 91910 | — |
| John Muir Physician Network | Concord | California | 94520 | — |
| John Muir Physicians Network | Concord | California | 94520 | — |
| Valley Research | Fresno | California | 93720 | — |
| California Institute of Renal Research | La Mesa | California | 91942 | — |
| First Valley Med Grp Lancaster | Lancaster | California | 93534 | — |
| Clinical Trials Research_Sacramento | Lincoln | California | 95648 | — |
| VA Loma Linda Hlthcr Sys | Loma Linda | California | 92357 | — |
| Long Beach Center For Clinical Research | Long Beach | California | 90807 | — |
| VA Long Beach Healthcare System | Long Beach | California | 90822 | — |
| Academic Medical Research Institute | Los Angeles | California | 90022 | — |
| Valley Renal Medical Group Research | Northridge | California | 91324 | — |
| Desert Oasis Hlthcr Med Group | Palm Springs | California | 92262 | — |
| Saviers Medical Group | Port Hueneme | California | 93041 | — |
| Inland Empire Clin Trials LLC | Rialto | California | 92377 | — |
| Sierra Clinical Research | Roseville | California | 95661 | — |
| California Research Foundation | San Diego | California | 92123 | — |
| N America Res Inst - San Dimas | San Dimas | California | 91773 | — |
| NorCal Endocrinology and Internal Medicine | San Ramon | California | 94583 | — |
| Lundquist Inst-Biomed Innovtn | Torrance | California | 90502 | — |
| San Fernando Valley Hlth Inst | West Hills | California | 91304 | — |
| Rocky Mount Reg VA Med-DN | Aurora | Colorado | 80045 | — |
| Creekside Endocrine Associates, PC | Denver | Colorado | 80246 | — |
| BayCare Medical Group - Endocrinology | Clearwater | Florida | 33756 | — |
| Horizon Rs Grp, Coral Gbls | Coral Gables | Florida | 33134 | — |
| Cesar Figueroa M.D. P.A. | Delray Beach | Florida | 33445 | — |
| Northeast Research Institute | Fleming Island | Florida | 32003 | — |
| Palmetto Medical General Plaza | Hialeah | Florida | 33016 | — |
| Encore Medical Research LLC | Hollywood | Florida | 33021 | — |
| Homestead Associates In Research | Homestead | Florida | 33032 | — |
| Life Spring Research | Miami | Florida | 33130 | — |
| Oceane 7 Medical & Research Center, Inc. | Miami | Florida | 33144 | — |
| International Physicians Research | Miami | Florida | 33173 | — |
| San Marcus Res Clin Miami Lakes | Miami Lakes | Florida | 33014 | — |
| Floridian Clinical Research, LLC | Miami Lakes | Florida | 33016 | — |
| South Broward Research LLC | Miramar | Florida | 33027 | — |
| Suncoast Clinical Research, Inc. | New Port Richey | Florida | 34652 | — |
| Hanson Clinical Research Center | Port Charlotte | Florida | 33952 | — |
| Northeast Research Institute | Saint Augustine | Florida | 32080 | — |
| Cardiovascular Ctr of Sarasota | Sarasota | Florida | 34239 | — |
| Clinical Research of Cent FL | Winter Haven | Florida | 33880 | — |
| Ellipsis Group | Alpharetta | Georgia | 30022 | — |
| Southeastern Clinical Research Institute, LLC | Augusta | Georgia | 30904 | — |
| Endocrine Research Solutions | Roswell | Georgia | 30076 | — |
| Solaris Clinical Research | Meridian | Idaho | 83646 | — |
| Saltzer Medical Group Research | Nampa | Idaho | 83686-6011 | — |
| Apex Medical Research Inc | Chicago | Illinois | 60607 | — |
| Clinical Invest Special_Gurnee | Gurnee | Illinois | 60031 | — |
| North Suburban Nephrology LLC | Gurnee | Illinois | 60031 | — |
| Endeavor Health | Skokie | Illinois | 60077 | — |
| Velocity Clin. Res Valparaiso | Valparaiso | Indiana | 46383 | — |
| West Broadway Clinic | Council Bluffs | Iowa | 51501 | — |
| Four Rivers Clinical Research Inc | Paducah | Kentucky | 42001 | — |
| Metropolitan Cardiovascular Consultants, LLC | Beltsville | Maryland | 20705 | — |
| Brigham & Women's Hospital | Boston | Massachusetts | 02115-5804 | — |
| Northern Pines Hlth Ctr, PC | Buckley | Michigan | 49620 | — |
| Aa Mrc Llc | Flint | Michigan | 48504 | — |
| Elite Research Center | Flint | Michigan | 48532 | — |
| Mayo Clinic | Rochester | Minnesota | 55905-0001 | — |
| Clinical Research Consultants, LLC | Kansas City | Missouri | 64111 | — |
| Washington University_St. Louis_0 | St Louis | Missouri | 63110 | — |
| Univ of Nebraska Medical CTR | Omaha | Nebraska | 68198 | — |
| Renal Medicine Associates | Albuquerque | New Mexico | 87109 | — |
| Albany Medical College - Endo | Albany | New York | 12203 | — |
| NYU Langone Neph Associates | Mineola | New York | 11501 | — |
| NYU Nephrology Associates | New York | New York | 10016 | — |
| Southgate Medical Group, LLP | West Seneca | New York | 14224 | — |
| UNC Diabetes Care Center_Chapel Hill | Chapel Hill | North Carolina | 27514 | — |
| Carteret Medical Group | Morehead City | North Carolina | 28557 | — |
| Burke Primary Care | Morganton | North Carolina | 28655 | — |
| Eastern Nephr Assoc, PLLC | New Bern | North Carolina | 28562 | — |
| Whiteville Medical Associates | Whiteville | North Carolina | 28472 | — |
| Accellacare | Wilmington | North Carolina | 28401 | — |
| Brookview Hills Research Associates, LLC | Winston-Salem | North Carolina | 27103 | — |
| Cincinnati Veterans Affairs Medical Center | Cincinnati | Ohio | 45220-2213 | — |
| Advanced Med Res Maumee | Maumee | Ohio | 43537 | — |
| Alliance for Multispec Res | Norman | Oklahoma | 73069 | — |
| Heritage Valley Medical Group Inc | Beaver | Pennsylvania | 15009 | — |
| Lycoming Internal Medicine, Inc. | Jersey Shore | Pennsylvania | 17740 | — |
| Northeast Endocrine Metabolic Associates | Philadelphia | Pennsylvania | 19114 | — |
| Main Street Physician's Care | Little River | South Carolina | 29566 | — |
| The Diabetes Center, LLC | Murrells Inlet | South Carolina | 29576 | — |
| Family Medicine of SayeBrook LLC | Myrtle Beach | South Carolina | 29588 | — |
| SC Nephrology and Hypertension | Orangeburg | South Carolina | 29118 | — |
| AM Diabetes And Endocrinology Center | Bartlett | Tennessee | 38133 | — |
| Univ Diab & Endo Consultants | Chattanooga | Tennessee | 37411 | — |
| Vanderbilt Medical Center_Nashville | Nashville | Tennessee | 37232 | — |
| Central Texas Clinical Research | Austin | Texas | 78705 | — |
| Texas Diabetes & Endocrinology, P.A._Austin | Austin | Texas | 78731 | — |
| Research Management, Inc | Austin | Texas | 78751 | — |
| Osvaldo A. Brusco MD PA | Corpus Christi | Texas | 78414 | — |
| Baylor Jack and Jane Hamilton | Dallas | Texas | 75226 | — |
| Research Institute Of Dallas | Dallas | Texas | 75231 | — |
| UT Southwestern Med Cntr | Dallas | Texas | 75390-9302 | — |
| MedResearch Inc | El Paso | Texas | 79902 | — |
| Academy of Diabetes, T&E | El Paso | Texas | 79935 | — |
| Juno Research, LLC_Houston | Houston | Texas | 77040 | — |
| Juno Research, LLC_Houston | Houston | Texas | 77074 | — |
| Southwest Clinical Trials | Houston | Texas | 77081 | — |
| Southwest Houston Research Ltd | Houston | Texas | 77099 | — |
| Carlos Arauz-Pacheco Md, Pa | Rockwall | Texas | 75032 | — |
| Univ Of Texas Hlth Science Cntr | San Antonio | Texas | 78207 | — |
| Sun Research Institute | San Antonio | Texas | 78215 | — |
| Briggs Clinical Research, LLC | San Antonio | Texas | 78224 | — |
| VIP Trials | San Antonio | Texas | 78230 | — |
| NE Clin Res of San Antonio | San Antonio | Texas | 78233 | — |
| Simcare Medical Research, LLC | Sugar Land | Texas | 77478 | — |
| University of Utah School of Medicine | Salt Lake City | Utah | 84108 | — |
| University of Vermont Medical Center | South Burlington | Vermont | 05403 | — |
| York Clinical Research LLC | Norfolk | Virginia | 23504 | — |
| McGuire VA Medical Center | Richmond | Virginia | 23249 | — |
| VA Medical Center_Salem | Salem | Virginia | 24153-6404 | — |
| Amherst Family Practice P.C. | Winchester | Virginia | 22601 | — |
| Capital Clin Res Ctr,LLC | Olympia | Washington | 98502 | — |
| MultiCare Inst for Res & Innov | Spokane | Washington | 99202 | — |
| Universal Research Group | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 296 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03819153, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 20, 2025 · Synced Oct 4, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03819153 live on ClinicalTrials.gov.