Efficacy and Safety of DaxibotulinumtoxinA for Injection for the Treatment of Adult Upper Limb Spasticity
Public ClinicalTrials.gov record NCT03821402. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Dose-Ranging, Multi-Center Trial to Evaluate the Efficacy and Safety of DaxibotulinumtoxinA for Injection for the Treatment of Upper Limb Spasticity in Adults After Stroke or Traumatic Brain Injury
Study identification
- NCT ID
- NCT03821402
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Revance Therapeutics, Inc.
- Industry
- Enrollment
- 83 participants
Conditions and interventions
Conditions
Interventions
- DAXI for injection 250 U Biological
- DAXI for injection 375 U Biological
- DAXI for injection 500 U Biological
- Placebo Other
Biological · Other
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 11, 2018
- Primary completion
- Nov 22, 2020
- Completion
- Nov 22, 2020
- Last update posted
- Sep 20, 2023
2018 – 2020
United States locations
- U.S. sites
- 26
- U.S. states
- 14
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Rancho Research Institute at Rancho Los Amigos National Rehab Center | Downey | California | 90242 | — |
| The Parkinsons and Movement Disorder Institute | Fountain Valley | California | 92708-5153 | — |
| Collaborative Neuroscience Network LLC | Long Beach | California | 90806 | — |
| SC3 Research | Pasadena | California | 91105 | — |
| Yale University | Fairfield | Connecticut | 06824-5340 | — |
| Waterbury Neurologists | Middlebury | Connecticut | 06762 | — |
| Ki Health Partners LLC DBA New England Institute for Clinical Research | Stamford | Connecticut | 06905-1206 | — |
| MedStar National Rehabilitation Hospital | Washington D.C. | District of Columbia | 20010 | — |
| Parkinsons Disease and Movement Disorders Center | Boca Raton | Florida | 33486 | — |
| NW FL Clinical Research Group, LLC | Gulf Breeze | Florida | 32561-4458 | — |
| Infinity Clinical Research | Hollywood | Florida | 33024 | — |
| Parkinsons Disease Treatment Center of Southwest Florida | Port Charlotte | Florida | 33980-8421 | — |
| Shirley Ryan AbilityLab | Chicago | Illinois | 60611-2654 | — |
| Kansas Institute of Research | Overland Park | Kansas | 66211-1358 | — |
| William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| Rusk Rehabilitation Hospital | Columbia | Missouri | 65203 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| Weill Cornell Medical College | New York | New York | 10065-4870 | — |
| Carolinas Rehabilitation | Charlotte | North Carolina | 28203 | — |
| Wake Forest University School of Medicine | Salem | North Carolina | 27157 | — |
| MossRehab | Elkins Park | Pennsylvania | 19027-2220 | — |
| University of Pittsburgh School of Medicine | Pittsburgh | Pennsylvania | 15213 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| North Texas Institute of Neurology and Headache | Frisco | Texas | 75034 | — |
| University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03821402, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 20, 2023 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03821402 live on ClinicalTrials.gov.