GAIN Trial: Phase 2/3 Study of COR388 in Subjects With Alzheimer's Disease
Public ClinicalTrials.gov record NCT03823404. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
GAIN Trial: A Randomized, Double-Blind, Placebo-Controlled Study of COR388 in Subjects With Alzheimer's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a randomized, double-blind, placebo-controlled study that assessed the efficacy, safety, and tolerability of 2 dose levels of COR388 in subjects with a clinical diagnosis of mild to moderate Alzheimer's disease (AD) dementia.
Study identification
- NCT ID
- NCT03823404
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 643 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 55 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 28, 2019 (Actual)
- Primary completion
- Jan 1, 2022 (Actual)
- Completion
- Jan 1, 2022 (Actual)
- Last update posted
- Feb 23, 2023
2019 – 2022
United States locations
- U.S. sites
- 58
- U.S. states
- 21
- U.S. cities
- 51
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Xenoscience, Inc. | Phoenix | Arizona | 85004 | — |
| Banner Alzheimer's Institute | Phoenix | Arizona | 85006 | — |
| Banner Sun Health | Sun City | Arizona | 85351 | — |
| ATP Clinical Research, Inc. | Costa Mesa | California | 92626 | — |
| Alliance Research | Long Beach | California | 90807 | — |
| Standford University | Palo Alto | California | 94305 | — |
| CITRIALS | Riverside | California | 92506 | — |
| CITRIALS | Santa Ana | California | 92705 | — |
| Syrentis Clinical Research | Santa Ana | California | 92705 | — |
| Southern California Research LLC | Simi Valley | California | 93065 | — |
| JEM Research Institute | Atlantis | Florida | 33462 | — |
| Brain Matters Research | Delray Beach | Florida | 33445 | — |
| Neuropsychiatric Research Center of Southwest Florida | Fort Myers | Florida | 33912 | — |
| MD Clinical | Hallandale | Florida | 33009 | — |
| Indago Research and Health Center, Inc. | Hialeah | Florida | 33012 | — |
| Alzheimer's Research and Treatment Center | Lake Worth | Florida | 33449 | — |
| Qtrials, Inc. | Miami | Florida | 33144 | — |
| Future Care Solutions, LLC | Miami | Florida | 33165 | — |
| Miami Dade Medical Research Institute | Miami | Florida | 33176 | — |
| Sensible Healthcare LLC | Ocoee | Florida | 34761 | — |
| Bioclinica Research | Orlando | Florida | 32806 | — |
| Anchor Neuroscience | Pensacola | Florida | 32502 | — |
| Suncoast Neuroscience Associates, Inc. | St. Petersburg | Florida | 33713 | — |
| Brain Matters Research at the Kane Center | Stuart | Florida | 34997 | — |
| Stedman Clinical Trials | Tampa | Florida | 33613 | — |
| Columus Memory Center | Columbus | Georgia | 31909 | — |
| NeuroStudies.net, LLC | Decatur | Georgia | 30033 | — |
| Northwest Clinical Trials | Boise | Idaho | 83704 | — |
| Alexian Brothers Neurosciences Research | Elk Grove Village | Illinois | 60007 | — |
| Ascension Via Christi Research | Wichita | Kansas | 67214 | — |
| Activmed Practices and Research | Methuen | Massachusetts | 01844 | — |
| The Boston Center for Memory | Newton | Massachusetts | 02459 | — |
| Anil Nair MD, Alzheimer's Disease Center | Quincy | Massachusetts | 02169 | — |
| Memory Center | Hattiesburg | Mississippi | 39401 | — |
| Cleveland Clinic Lou Ruvo Center for Brain Health | Las Vegas | Nevada | 89106 | — |
| Princeton Medical Institute | Princeton | New Jersey | 08540 | — |
| The Cognitive Research Center of New Jersey | Springfield | New Jersey | 07081 | — |
| Neurology Specialists of Monmouth County | West Long Branch | New Jersey | 07764 | — |
| Albuquerque Neuroscience | Albuquerque | New Mexico | 87109 | — |
| Disease Research & Neurology Center of Neurological Associates of Albany | Albany | New York | 12208 | — |
| Integrative Clinical Trials LLC | Brooklyn | New York | 11229 | — |
| Spri Clinicaltrials, Llc | Brooklyn | New York | 11235 | — |
| Mid Hudson Medical Research | New Windsor | New York | 12553 | — |
| ANI Neurology, PLLC dba Alzheimer's Memory Center | Charlotte | North Carolina | 28270 | — |
| Insight Clinical Trials, LLC | Beachwood | Ohio | 44122 | — |
| Neurology Diagnostics Inc. | Dayton | Ohio | 45459 | — |
| Memory Health Center at Summit Research Network | Portland | Oregon | 97210 | — |
| Northeastern Pennsylvania Memory and Alzheimer's Center | Plains | Pennsylvania | 18507 | — |
| Senior Adults Specialty Research | Austin | Texas | 78757 | — |
| Kerwin Research Center | Dallas | Texas | 75231 | — |
| Neurology Consultants of Dallas | Dallas | Texas | 75243 | — |
| Houston Methodist Department of Neurology | Houston | Texas | 77030 | — |
| Clinical Trial Network | Houston | Texas | 77074 | — |
| University of Virginia Adult Neurology | Charlottesville | Virginia | 22903 | — |
| Recognition Health | Fairfax | Virginia | 22031 | — |
| Northwest Clinical Research Center | Bellevue | Washington | 98007 | — |
| UW Alzheimer's Disease Research Center | Seattle | Washington | 98104 | — |
| Medical College of Wisconsin, Inc. | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 35 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03823404, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 23, 2023 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03823404 live on ClinicalTrials.gov.