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Completed Phase 1Phase 2 Interventional Results available

Study of Intravenous ATYR1923 (Efzofitimod) for Pulmonary Sarcoidosis

ClinicalTrials.gov ID: NCT03824392

Public ClinicalTrials.gov record NCT03824392. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 8:19 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled Multiple Ascending Dose Study of Intravenous ATYR1923 in Patients With Pulmonary Sarcoidosis

Study identification

NCT ID
NCT03824392
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
aTyr Pharma, Inc.
Industry
Enrollment
37 participants

Conditions and interventions

Interventions

  • Efzofitimod 1.0 mg/kg or Placebo Biological
  • Efzofitimod 3.0 mg/kg or Placebo Biological
  • Efzofitimod 5.0 mg/kg or Placebo Biological

Biological

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 28, 2019
Primary completion
Jun 28, 2021
Completion
Jun 28, 2021
Last update posted
Jul 17, 2023

2019 – 2021

United States locations

U.S. sites
15
U.S. states
13
U.S. cities
14
Facility City State ZIP Site status
University of Alabama Birmingham Alabama 35294-0006
aTyr Investigative Site Northridge California 91324
National Jewish Health Denver Colorado 80206
aTyr Investigative Site Miami Florida 33125
Emory University Atlanta Georgia 30322
Northwestern University Chicago Illinois 60611
aTyr Investigative Site Chicago Illinois 60612
University of Iowa Iowa City Iowa 52242
University of Louisville Louisville Kentucky 40202
East Carolina University Greenville North Carolina 27858
University of Cincinnati Cincinnati Ohio 45267
Cleveland Clinic Cleveland Ohio 44195
Medical University of South Carolina Charleston South Carolina 92425
UT Southwestern Medical Center Dallas Texas 75390
Inova Fairfax Medical Center Falls Church Virginia 22042

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03824392, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 17, 2023 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03824392 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →