Study to Evaluate the Efficacy of Tenapanor as Adjunctive Therapy to Phosphate Binder Therapy
Public ClinicalTrials.gov record NCT03824587. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy of Tenapanor as Adjunctive Therapy to Phosphate Binder Therapy in End-Stage Renal Disease (ESRD) Subjects With Hyperphosphatemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a randomized, double-blind, placebo-controlled study to evaluate the effect of tenapanor on change in s-P levels when tenapanor is administered orally, twice daily for 28 days as adjunctive therapy to ESRD subjects with hyperphosphatemia on stable phosphate binder therapy.
Study identification
- NCT ID
- NCT03824587
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 236 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2019 (Actual)
- Primary completion
- Jul 17, 2019 (Actual)
- Completion
- Jul 17, 2019 (Actual)
- Last update posted
- Mar 6, 2023
2019
United States locations
- U.S. sites
- 48
- U.S. states
- 22
- U.S. cities
- 44
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Nephrology Consultants, LLC | Huntsville | Alabama | 35805 | — |
| US Renal Care Pine Bluff | Pine Bluff | Arkansas | 71603 | — |
| Southeast Renal Research | Beverly Hills | California | 90211 | — |
| California Institute of Renal Research - Chula Vista | Chula Vista | California | 91910 | — |
| North America Research Institute | Lynwood | California | 90262 | — |
| DaVita Clinical Research - Santa Fe Spring | Montebello | California | 90640 | — |
| Central Coast Nephrology | Salinas | California | 93901 | — |
| North America Research Institute - San Dimas | San Dimas | California | 91773 | — |
| Chabot Nephrology Medical Group | Union City | California | 94587 | — |
| American Institute of Research | Whittier | California | 90603 | — |
| Nova Clinical Research, LLC | Bradenton | Florida | 34209 | — |
| Horizon Research Group - Coral Gables | Coral Gables | Florida | 33134 | — |
| South Florida Research Institute | Lauderdale Lakes | Florida | 33313 | — |
| Total Research Group, LLC | Miami | Florida | 33126 | — |
| Omega Research Consultants, LLC | Orlando | Florida | 32810 | — |
| Genesis Clinical Trials | Tampa | Florida | 33614 | — |
| Dialysis Clinic, Inc - Albany GA | Albany | Georgia | 31701 | — |
| Boise Kidney & Hypertension, PLLC - Meridian | Caldwell | Idaho | 83605 | — |
| Renal Associates of Baton Rouge | Baton Rouge | Louisiana | 70808 | — |
| Dialysis Clinic, Inc - Boston/Somerville | Boston | Massachusetts | 02111 | — |
| Paragon Health PC - Nephrology Center | Kalamazoo | Michigan | 49007 | — |
| InterMed Consultants | Minneapolis | Minnesota | 55404 | — |
| Nephrology and Hypertension Associates, LTD | Tupelo | Mississippi | 38801 | — |
| Clinical Research Consultants, LLC | Kansas City | Missouri | 64111 | — |
| Dialysis Clinic, Inc - Kansas City | Kansas City | Missouri | 64131 | — |
| Polack Renal, LLC (SMO) | St Louis | Missouri | 63121 | — |
| Kidney Specialists of Southern Nevada | Las Vegas | Nevada | 89107 | — |
| Sierra Nevada Nephrology Consultants | Reno | Nevada | 89511 | — |
| Dialysis Clinic, Inc - North Brunswick | North Brunswick | New Jersey | 08902 | — |
| Renal Medicine Associates | Albuquerque | New Mexico | 87109 | — |
| U.S. Renal Care - Gallup | Gallup | New Mexico | 87301 | — |
| Northwell Health | Great Neck | New York | 11021 | — |
| Mountain Kidney and Hypertension Associates | Asheville | North Carolina | 28801 | — |
| Mountain Kidney & Hypertension Associates, P.A. | Asheville | North Carolina | 28805 | — |
| Durham Nephrology Associates | Durham | North Carolina | 27704 | — |
| Southeastern Nephrology Associates - Wilmington | Wilmington | North Carolina | 28401 | — |
| University of Cincinnati (UC) - Department of Nephrology | Cincinnati | Ohio | 45267 | — |
| Northeast Clinical Research Center | Bethlehem | Pennsylvania | 18017 | — |
| Columbia Nephrology Associates, P.A. | Columbia | South Carolina | 29203 | — |
| South Carolina Nephrology & Hypertension Center Inc. | Orangeburg | South Carolina | 29118 | — |
| DCI - Spartanburg | Spartanburg | South Carolina | 29301 | — |
| Knoxville Kidney Center, PLLC | Knoxville | Tennessee | 37923 | — |
| Med Center Dialysis | Houston | Texas | 77004 | — |
| US Renal Care - Waxahachie | Mansfield | Texas | 76063 | — |
| US Renal Care - Mesquite | Mesquite | Texas | 75150 | — |
| Clinical Advancement Center, PLLC | San Antonio | Texas | 78212 | — |
| US Renal Care - Pleasanton Road | San Antonio | Texas | 78221 | — |
| US Renal Care - Westover Hills | San Antonio | Texas | 78251 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03824587, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 6, 2023 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03824587 live on ClinicalTrials.gov.