A Study of Semorinemab in Patients With Moderate Alzheimer's Disease
Public ClinicalTrials.gov record NCT03828747. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy, and Safety Study of MTAU9937A in Patients With Moderate Alzheimer's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This Phase II, multicenter, randomized, double-blind, placebo-controlled, parallel-group study will evaluate the clinical efficacy, safety, pharmacokinetics, and pharmacodynamics of semorinemab in patients with moderate AD. The study consists of a screening period, a double-blind treatment period, an optional open-label extension (OLE) period, and a safety follow-up period. There may be up to two study cohorts.
Study identification
- NCT ID
- NCT03828747
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 272 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 25, 2019 (Actual)
- Primary completion
- Jul 20, 2021 (Actual)
- Completion
- Aug 30, 2023 (Actual)
- Last update posted
- Sep 24, 2024
2019 – 2023
United States locations
- U.S. sites
- 31
- U.S. states
- 13
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Collaborative Neuroscience Network, Inc. | Garden Grove | California | 92845 | — |
| Pharmacology Research Institute | Los Alamitos | California | 90720 | — |
| Stanford University; Stanford Clinical Cancer Ctr | Palo Alto | California | 94305 | — |
| Pacific Research Network - PRN | San Diego | California | 92103 | — |
| Molecular Neuroimaging; MRI/PET | New Haven | Connecticut | 06510 | — |
| KI Health Partners, LLC; New England Institute for Clinical Research | Stamford | Connecticut | 06905 | — |
| JEM Research LLC | Atlantis | Florida | 33462 | — |
| Bradenton Research Center | Bradenton | Florida | 34205 | — |
| Brain Matters Research, Inc. | Delray Beach | Florida | 33445 | — |
| Neuropsychiatric Research; Center of Southwest Florida | Fort Myers | Florida | 33912 | — |
| Miami Jewish Health Systems | Miami | Florida | 33137 | — |
| Collier Neurologic Specialists | Naples | Florida | 34105 | — |
| Synexus Clinical Research US, Inc. - Orlando | Orlando | Florida | 32806 | — |
| Alzheimer?s Research and Treatment Center | Wellington | Florida | 33414 | — |
| Premiere Research Institute | West Palm Beach | Florida | 33407 | — |
| Rush University Medical Center - Chicago | Chicago | Illinois | 60612 | — |
| Alexian Brothers Neuroscience Institute | Elk Grove Village | Illinois | 60007 | — |
| Southern Illinois University, School of Medicine | Springfield | Illinois | 62702 | — |
| Brigham and Womens Hospital; Center for Alzheimer Research & Treatment | Boston | Massachusetts | 02115 | — |
| Alzheimers Disease Center | Quincy | Massachusetts | 02169 | — |
| Center for Memory and Aging | Saint Paul | Minnesota | 55130 | — |
| Advanced Memory Research Institute of NJ | Toms River | New Jersey | 08755 | — |
| Empire Neurology PC; MS Center of Northeastern NY | Latham | New York | 12110 | — |
| University of Rochester; AD-CARE | Rochester | New York | 14642 | — |
| Summit Research Network Inc. | Portland | Oregon | 97210 | — |
| Abington Neurological Associates | Abington | Pennsylvania | 19001 | — |
| Rhode Island Mood & Memory Research Institute | East Providence | Rhode Island | 02914 | — |
| Butler Hospital; Movement Disorders Program | Providence | Rhode Island | 02906 | — |
| Neurology Clinic PC | Cordova | Tennessee | 38018 | — |
| New Orleans Center for Clinical Research | Knoxville | Tennessee | 37920 | — |
| The Memory Clinic | Bennington | Vermont | 05201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 18 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03828747, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 24, 2024 · Synced Oct 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03828747 live on ClinicalTrials.gov.