A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)
Public ClinicalTrials.gov record NCT03834753. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Clinical Effectiveness, Multicenter, Randomized, Double-masked, Controlled Study of the Efficacy and Safety of ONS-5010 in Subjects With Subfoveal Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This research study will examine the safety and effectiveness of ONS-5010 in participants with AMD. The goal is to prevent vision loss by evaluating the effectiveness of ONS-5010 as compared with ranibizumab.
Study identification
- NCT ID
- NCT03834753
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 228 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 25, 2019 (Actual)
- Primary completion
- Jun 7, 2021 (Actual)
- Completion
- Jul 8, 2021 (Actual)
- Last update posted
- Aug 3, 2026
2019 – 2021
United States locations
- U.S. sites
- 50
- U.S. states
- 21
- U.S. cities
- 49
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Site | Tucson | Arizona | 85710 | — |
| Clinical Site | Arcadia | California | 91007 | — |
| Clinical Site | Beverly Hills | California | 90211 | — |
| Clinical Site | Campbell | California | 95008 | — |
| Clinical Site | Glendale | California | 91203 | — |
| Clinical Site | Laguna Hills | California | 92653 | — |
| Clinical Site | Long Beach | California | 90807 | — |
| Clinical Site | Mountain View | California | 94040 | — |
| Clinical Site | Oxnard | California | 93036 | — |
| Clinical Site | Palm Desert | California | 92260 | — |
| Clinical Site | Poway | California | 92064 | — |
| Clinical Site | Sacramento | California | 95841 | — |
| Clinical Site | Santa Maria | California | 93454 | — |
| Clinical Site | Tustin | California | 92780 | — |
| Clinical Site | Golden | Colorado | 80401 | — |
| Clinical Site | Hamden | Connecticut | 06518 | — |
| Clinical Site | Clearwater | Florida | 33761 | — |
| Clinical Site | Pinellas Park | Florida | 33782 | — |
| Clinical Site | Sarasota | Florida | 24233 | — |
| Clinical Site | Winter Haven | Florida | 33880 | — |
| Clinical Site | Augusta | Georgia | 30909 | — |
| Clinical Site | Marietta | Georgia | 30060 | — |
| Clinical Site | Downers Grove | Illinois | 60615 | — |
| Clinical Site | Lemont | Illinois | 60439 | — |
| Clinical Site | Springfield | Illinois | 62704 | — |
| Clinical Site | Indianapolis | Indiana | 46290 | — |
| Clinical Site | Hagerstown | Maryland | 21740 | — |
| Clinical Site | Edina | Minnesota | 55435 | — |
| Clinical Site | St Louis | Missouri | 63144 | — |
| Clinical Site | Bloomfield | New Jersey | 07003 | — |
| Clinical Site | Albuquerque | New Mexico | 87109 | — |
| Clinical Site | New York | New York | 10021 | — |
| Clinical Site | Chambersburg | Pennsylvania | 17201 | — |
| Clinical Site | Monroeville | Pennsylvania | 15146 | — |
| Clinical Site | Rapid City | South Dakota | 57701 | — |
| Clinical Site | Germantown | Tennessee | 38138 | — |
| Clinical Site | Abilene | Texas | 79606 | — |
| Clinical Site | Amarillo | Texas | 79106 | — |
| Clinical Site | Arlington | Texas | 76012 | — |
| Clinical Site | Dallas | Texas | 75231 | — |
| Clinical Site | Grapevine | Texas | 76051 | — |
| Clinical Site | Houston | Texas | 77030 | — |
| Clinical Site | McAllen | Texas | 78503 | — |
| Clinical Site | San Antonio | Texas | 78240 | — |
| Clinical Site | San Antonio | Texas | 78251 | — |
| Clinical Site | The Woodlands | Texas | 77384 | — |
| Clinical Site | Willow Park | Texas | 76807 | — |
| Clinical Site | Salt Lake City | Utah | 84107 | — |
| Clinical Site | Norfolk | Virginia | 23502 | — |
| Clinical Site | Madison | Wisconsin | 53705 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03834753, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 3, 2026 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03834753 live on ClinicalTrials.gov.