M7824 With cCRT in Unresectable Stage III Non-small Cell Lung Cancer (NSCLC)
Public ClinicalTrials.gov record NCT03840902. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Double Blind, Randomized, Controlled Study of M7824 With Concurrent Chemoradiation Followed by M7824 Versus Concurrent Chemoradiation Plus Placebo Followed by Durvalumab in Participants With Unresectable Stage III Non-small Cell Lung Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study was to evaluate safety and efficacy in participants treated with concomitant chemoradiation therapy (cCRT) plus M7824 followed by M7824 compared to cCRT plus placebo followed by durvalumab.
Study identification
- NCT ID
- NCT03840902
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 153 participants
Conditions and interventions
Conditions
Interventions
- M7824 Drug
- Placebo Drug
- Durvalumab Drug
- Etoposide Drug
- Pemetrexed Drug
- Carboplatin Drug
- Paclitaxel Drug
- Cisplatin Drug
- Intensity Modulated Radiation Therapy (IMRT) Radiation
Drug · Radiation
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 16, 2019 (Actual)
- Primary completion
- Feb 17, 2023 (Actual)
- Completion
- Feb 17, 2023 (Actual)
- Last update posted
- Jan 16, 2024
2019 – 2023
United States locations
- U.S. sites
- 21
- U.S. states
- 15
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of California Irvine Medical Center | Orange | California | 92868 | — |
| UCLA Hematology Oncology - Main Site - 2020 Santa Monica | Santa Monica | California | 90404 | — |
| University of Colorado Health - Memorial Hospital - Memorial Hospital | Colorado Springs | Colorado | 80909 | — |
| Hematology Oncology Associates | Fort Collins | Colorado | 80528 | — |
| Lynn Cancer Institute Center | Boca Raton | Florida | 33486 | — |
| Holy Cross Hospital - Michael and Dianne Bienes CCC | Fort Lauderdale | Florida | 33308 | — |
| Sylvester Comprehensive Cancer Center - University of Miami Health System | Miami | Florida | 33136 | — |
| The University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| American Health Network of Indiana, LLC | Indianapolis | Indiana | 46202 | — |
| Franciscan St. Francis Health Cancer Center | Indianapolis | Indiana | 46237 | — |
| Baptist Health Lexington Oncology Associates | Lexington | Kentucky | 40503 | — |
| University of Maryland - DUPLICATE/Pediatric Surgery | Baltimore | Maryland | 21201 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Mayo Clinic | Rochester | Minnesota | 55902 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Hematology Oncology Center of Nyack Hospital | Nyack | New York | 10960 | — |
| FirstHealth of the Carolinas, Inc. | Pinehurst | North Carolina | 28374 | — |
| The James Cancer Hospital and Solove Research Institute | Columbus | Ohio | 43210 | — |
| UPMC Cancer Center | Pittsburgh | Pennsylvania | 15232 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| University of Texas MD Anderson Cancer Center - Unit 432 Thoracic Head and Neck Medical Oncology | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 83 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03840902, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 16, 2024 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03840902 live on ClinicalTrials.gov.