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Terminated Phase 2 Interventional Results available

M7824 With cCRT in Unresectable Stage III Non-small Cell Lung Cancer (NSCLC)

ClinicalTrials.gov ID: NCT03840902

Public ClinicalTrials.gov record NCT03840902. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 6, 2026, 8:32 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Double Blind, Randomized, Controlled Study of M7824 With Concurrent Chemoradiation Followed by M7824 Versus Concurrent Chemoradiation Plus Placebo Followed by Durvalumab in Participants With Unresectable Stage III Non-small Cell Lung Cancer

Study identification

NCT ID
NCT03840902
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
EMD Serono Research & Development Institute, Inc.
Industry
Enrollment
153 participants

Conditions and interventions

Interventions

  • Carboplatin Drug
  • Cisplatin Drug
  • Durvalumab Drug
  • Etoposide Drug
  • Intensity Modulated Radiation Therapy (IMRT) Radiation
  • M7824 Drug
  • Paclitaxel Drug
  • Pemetrexed Drug
  • Placebo Drug

Drug · Radiation

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 15, 2019
Primary completion
Feb 16, 2023
Completion
Feb 16, 2023
Last update posted
Jan 15, 2024

2019 – 2023

United States locations

U.S. sites
21
U.S. states
15
U.S. cities
20
Facility City State ZIP Site status
University of California Irvine Medical Center Orange California 92868
UCLA Hematology Oncology - Main Site - 2020 Santa Monica Santa Monica California 90404
University of Colorado Health - Memorial Hospital - Memorial Hospital Colorado Springs Colorado 80909
Hematology Oncology Associates Fort Collins Colorado 80528
Lynn Cancer Institute Center Boca Raton Florida 33486
Holy Cross Hospital - Michael and Dianne Bienes CCC Fort Lauderdale Florida 33308
Sylvester Comprehensive Cancer Center - University of Miami Health System Miami Florida 33136
The University of Chicago Medical Center Chicago Illinois 60637
American Health Network of Indiana, LLC Indianapolis Indiana 46202
Franciscan St. Francis Health Cancer Center Indianapolis Indiana 46237
Baptist Health Lexington Oncology Associates Lexington Kentucky 40503
University of Maryland - DUPLICATE/Pediatric Surgery Baltimore Maryland 21201
Henry Ford Health System Detroit Michigan 48202
Mayo Clinic Rochester Minnesota 55902
Columbia University Medical Center New York New York 10032
Hematology Oncology Center of Nyack Hospital Nyack New York 10960
FirstHealth of the Carolinas, Inc. Pinehurst North Carolina 28374
The James Cancer Hospital and Solove Research Institute Columbus Ohio 43210
UPMC Cancer Center Pittsburgh Pennsylvania 15232
Vanderbilt University Medical Center Nashville Tennessee 37232
University of Texas MD Anderson Cancer Center - Unit 432 Thoracic Head and Neck Medical Oncology Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 83 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03840902, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 15, 2024 · Synced May 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03840902 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →