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Completed Phase 1Phase 2 Interventional Results available

M7824 in Combination With Chemotherapy in Stage IV Non-small Cell Lung Cancer (NSCLC)

ClinicalTrials.gov ID: NCT03840915

Public ClinicalTrials.gov record NCT03840915. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 8, 2026, 8:10 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase Ib/II, Open-Label Study of M7824 in Combination With Chemotherapy in Participants With Stage IV Non-small Cell Lung Cancer

Study identification

NCT ID
NCT03840915
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
EMD Serono Research & Development Institute, Inc.
Industry
Enrollment
70 participants

Conditions and interventions

Interventions

  • Bintrafusp alfa Drug
  • Carboplatin Drug
  • Cisplatin Drug
  • Docetaxel Drug
  • Gemcitabine Drug
  • M7824 Drug
  • Nab-paclitaxel Drug
  • Paclitaxel Drug
  • Pemetrexed Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 1, 2019
Primary completion
Jul 28, 2022
Completion
Jul 28, 2022
Last update posted
Aug 20, 2023

2019 – 2022

United States locations

U.S. sites
8
U.S. states
6
U.S. cities
8
Facility City State ZIP Site status
Compassionate Care Research Group Inc - Edinger Medical Group, Inc. Fountain Valley California 92708
California Cancer Associates for Research & Excellence, Inc. San Marcos California 92069
Hematology - Oncology Associates of Treasure Coast - Hematology-Oncology Associates of Treasure Coast Port Saint Lucie Florida 34952
Baptist Health Lexington Oncology Associates Lexington Kentucky 40503
University of Maryland - DUPLICATE/Pediatric Surgery Baltimore Maryland 21201
RCCA MD LLC - Bethesda Bethesda Maryland 20817
Henry Ford Health System Detroit Michigan 48202
Vanderbilt University Medical Center Nashville Tennessee 37232-8805

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03840915, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 20, 2023 · Synced May 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03840915 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →