A Study of Lanadelumab in Persons With Hereditary Angioedema (HAE) Type I or II in North America
Public ClinicalTrials.gov record NCT03845400. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
An Observational, Non-interventional, Study of Patients With Hereditary Angioedema in the United States and Canada (EMPOWER Study)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main aim of this study is to compare the HAE attack rate before and after lanadelumab treatment was started in persons with Hereditary Angioedeme Type I or II. Data from participants will be collected for at least 24 months. Participants will report information in a smartphone application at study start and then every 3 months until the study ends; data will also be collected by the study doctor during routine clinic visits.
Study identification
- NCT ID
- NCT03845400
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 168 participants
Conditions and interventions
Conditions
Interventions
Not listed
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 30, 2019 (Actual)
- Primary completion
- Oct 22, 2022 (Actual)
- Completion
- Oct 22, 2022 (Actual)
- Last update posted
- Mar 30, 2023
2019 – 2022
United States locations
- U.S. sites
- 23
- U.S. states
- 20
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Research Center of Alabama | Birmingham | Alabama | 35209 | — |
| Medical Research of Arizona | Scottsdale | Arizona | 85248 | — |
| University of California San Diego | San Diego | California | 92122 | — |
| AIRE Medical of Los Angeles | Santa Monica | California | 90404 | — |
| Asthma and Allergy Associates, PC | Colorado Springs | Colorado | 80907 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06519 | — |
| University of South Florida Asthma, Allergy & Immunology | Tampa | Florida | 33613 | — |
| University of Kansas Medical Center Research Institute, Inc. | Kansas City | Kansas | 66160 | — |
| Institute for Asthma & Allergy - Chevy Chase | Chevy Chase | Maryland | 20815 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114-2752 | — |
| University of Michigan | Ann Arbor | Michigan | 48106 | — |
| Mid West Immunology Clinic | Plymouth | Minnesota | 55446 | — |
| Washington University | St Louis | Missouri | 63141 | — |
| Riverside Medical Group, Belleville | Belleville | New Jersey | 07109 | — |
| Jay M Kashkin, MD Allergy, Asthma and Immunology | Fair Lawn | New Jersey | 07410 | — |
| Mount Sinai | New York | New York | 10029 | — |
| Clinical Research of Charlotte | Charlotte | North Carolina | 28277 | — |
| Duke Asthma, Allergy & Airway Center | Durham | North Carolina | 27704 | — |
| Bernstein Clinical Research Center, LLC | Cincinnati | Ohio | 45231 | — |
| Portland Clinical Research/AAIM Care | Happy Valley | Oregon | 97086 | — |
| Penn State Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| AARA Research Center | Dallas | Texas | 75231 | — |
| Seattle Allergy & Asthma Research Institute | Seattle | Washington | 98115 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03845400, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 30, 2023 · Synced Nov 6, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03845400 live on ClinicalTrials.gov.