A DOSE-RANGING STUDY TO EVALUATE EFFICACY AND SAFETY OF PF-06700841 IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Public ClinicalTrials.gov record NCT03845517. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 2B, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED, MULTICENTER, DOSE-RANGING STUDY TO EVALUATE THE EFFICACY AND SAFETY PROFILE OF PF-06700841 IN PARTICIPANTS WITH ACTIVE SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Assessment of PF-06700841 in participants with moderate to severe active, generalized Systemic Lupus Erythematosus (SLE) that have inadequate response to standard of care.
Study identification
- NCT ID
- NCT03845517
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 350 participants
Conditions and interventions
Conditions
Interventions
- Placebo Drug
- PF-06700841 15 mg Drug
- PF-06700841 30 mg Drug
- PF-06700841 45 mg Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 18, 2019 (Actual)
- Primary completion
- Oct 5, 2023 (Actual)
- Completion
- Oct 5, 2023 (Actual)
- Last update posted
- Sep 5, 2024
2019 – 2023
United States locations
- U.S. sites
- 55
- U.S. states
- 16
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UAB Department of Medicine Clinical Research Enterprise | Birmingham | Alabama | 35205 | — |
| The Kirklin Clinic | Birmingham | Alabama | 35233 | — |
| UAB Hospital Department of Pharmacy | Birmingham | Alabama | 35249 | — |
| UAB Hospital-Clinical Research Unit (CRU) | Birmingham | Alabama | 35249 | — |
| The University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| UAB Department of Medicine Clinical Research Enterprise | Birmingham | Alabama | 35294 | — |
| St. Joseph Heritage Healthcare | Fullerton | California | 92835 | — |
| Advanced Medical Research, LLC | La Palma | California | 90623 | — |
| Arthritis and Osteoporosis Medical Center | La Palma | California | 90623 | — |
| Desert Medical Advances | Palm Desert | California | 92260-9368 | — |
| East Bay Rheumatology Medical Group, Inc. | San Leandro | California | 94578 | — |
| Millennium Clinical Trials | Thousand Oaks | California | 91360 | — |
| Inland Rheumatology and Osteoporosis Medical Group | Upland | California | 91786 | — |
| Inland Rheumatology Clinical Trials, Inc. | Upland | California | 91786 | — |
| New England Research Associates, LLC | Bridgeport | Connecticut | 06606 | — |
| New England Research Associates | Bridgeport | Connecticut | 06606 | — |
| Stamford Therapeutics Consortium | Stamford | Connecticut | 06905 | — |
| Clinical Research of West Florida | Clearwater | Florida | 33765 | — |
| Private Practice of Robert W. Levin | Clearwater | Florida | 33765 | — |
| SIMEDHealth, LLC Attn: Rheumatology | Gainesville | Florida | 32607 | — |
| SIMEDHealth, LLC | Gainesville | Florida | 32607 | — |
| Omega Research MetroWest, LLC | Orlando | Florida | 32808 | — |
| Akumin, Inc | Palm Harbor | Florida | 34685 | — |
| Akumin Inc | St. Petersburg | Florida | 33703 | — |
| West Broward Rheumatology Associates, Inc | Tamarac | Florida | 33321 | — |
| Akumin Inc. | Tampa | Florida | 33603 | — |
| Rose Radiology dba Akumin Inc. | Tampa | Florida | 33603 | — |
| Clinical Research of West Florida | Tampa | Florida | 33606 | — |
| AdventHealth Tampa | Tampa | Florida | 33613 | — |
| Jefrey D. Lieberman, M.D., P.C. | Decatur | Georgia | 30033 | — |
| Atlanta Research Center for Rheumatology | Marietta | Georgia | 30060 | — |
| Institute of Arthritis Research | Idaho Falls | Idaho | 83404 | — |
| Investigational Drug Services University of Kansas Hospital | Kansas City | Kansas | 66103 | — |
| The University of Kansas Hospital | Kansas City | Kansas | 66160 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Ochsner Clinic Foundation, Baton Rouge | Baton Rouge | Louisiana | 70836 | — |
| University of Michigan Brighton Center for Specialty Care | Brighton | Michigan | 48116 | — |
| Innovative health Research | Las Vegas | Nevada | 89128 | — |
| NYU Langone Ambulatory Care Brooklyn Heights | Brooklyn | New York | 11201 | — |
| St. Lawrence Health System | Canton | New York | 13617 | — |
| Feinstein Institute for Medical Research | Manhasset | New York | 11030 | — |
| Northshore University Hospital | Manhasset | New York | 11030 | — |
| Columbia University Medical Center. | New York | New York | 10032 | — |
| Irving Institute for Clinical and Transitional Research | New York | New York | 10032 | — |
| St. Lawrence Health System | Potsdam | New York | 13676 | — |
| Joint and Muscle Research Institute | Charlotte | North Carolina | 28204 | — |
| Arthritis & Rheumatology Center of Oklahoma PLLC | Oklahoma City | Oklahoma | 73102 | — |
| West Tennessee Research Institute | Jackson | Tennessee | 38305 | — |
| Gupta, Ramesh C MD | Memphis | Tennessee | 38119-5214 | — |
| Tekton Research | Austin | Texas | 78745 | — |
| Accurate Clinical Management, LLC | Baytown | Texas | 77521 | — |
| Rheumatic Disease Clinical Research Center, LLC | Houston | Texas | 77004 | — |
| Accurate Clinical Research | Houston | Texas | 77089 | — |
| Arthritis Clinic of Central Texas | San Marcos | Texas | 78666 | — |
| Arthritis Northwest, PLLC | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 109 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03845517, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 5, 2024 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03845517 live on ClinicalTrials.gov.