Establishing the Safety and Efficacy of Reloxaliase in Patients With Enteric Hyperoxaluria
Public ClinicalTrials.gov record NCT03847090. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Establishing the Safety and Efficacy of Reloxaliase (Oxalate Decarboxylase) in Patients With Enteric Hyperoxaluria: A Phase III Randomized, Double-Blind, Placebo-Controlled Study (URIROX-2)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the efficacy, durability and long-term safety of reloxaliase in patients with enteric hyperoxaluria.
Study identification
- NCT ID
- NCT03847090
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 92 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 26, 2019 (Actual)
- Primary completion
- May 19, 2022 (Actual)
- Completion
- May 19, 2022 (Actual)
- Last update posted
- Jun 10, 2022
2019 – 2022
United States locations
- U.S. sites
- 64
- U.S. states
- 30
- U.S. cities
- 60
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama- Department of Urology | Birmingham | Alabama | 35234 | — |
| Alliance for Multispecialty Research, LLC | Mobile | Alabama | 36608 | — |
| Aventiv Research Inc. | Mesa | Arizona | 85210 | — |
| Arizona Kidney Disease and Hypertension Center (AKDHC)- Phoenix | Peoria | Arizona | 85381 | — |
| Arizona Kidney Disease and Hypertension Center (AKDHC)- Glendale | Phoenix | Arizona | 85016 | — |
| Mayo Mercy Hospital | Phoenix | Arizona | 85054 | — |
| Urological Associates of Southern Arizona | Tucson | Arizona | 85715 | — |
| Banner University Medical Center | Tucson | Arizona | 85724 | — |
| Arkansas Urology | Little Rock | Arkansas | 72211 | — |
| Applied Research Center of Arkansas | Little Rock | Arkansas | 72212 | — |
| Renal Consultants Medical Group | Granada Hills | California | 91344 | — |
| Amicis Research | Northridge | California | 91324 | — |
| University of California, San Diego (UCSD) Health System | San Diego | California | 92103 | — |
| University of California- San Francisco (UCSF) | San Francisco | California | 94143 | — |
| Stanford University School of Medicine | Stanford | California | 94305 | — |
| Sutter Health- Sacramento | Vacaville | California | 95688 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06510 | — |
| South Florida Nephrology Group PA Research Div | Coral Springs | Florida | 33071 | — |
| University of Florida College of Medicine | Gainesville | Florida | 32610 | — |
| Quantum Clinical Research | Hialeah | Florida | 33012 | — |
| Mayo Clinic | Jacksonville | Florida | 32224 | — |
| Pro-Care Research Center, Corp | Miami Gardens | Florida | 33014 | — |
| Avanza Medical Research Center | Pensacola | Florida | 32503 | — |
| University of South Florida | Tampa | Florida | 33606 | — |
| Idaho Catalyst Clinical Research | Idaho Falls | Idaho | 83404 | — |
| Idaho Urologic Institute | Meridian | Idaho | 83642 | — |
| IU Health Physicians | Carmel | Indiana | 46032 | — |
| Indiana University (IU) Nephrology | Indianapolis | Indiana | 46202 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Regional Urology | Shreveport | Louisiana | 71106 | — |
| Chesapeake Urology Associates, LLC d/b/a/ Chesapeake Urology Research Associates | Glen Burnie | Maryland | 21061 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| University of Michigan | Ann Arbor | Michigan | 48084 | — |
| Mayo Clinic- Department of Nephrology Hyperoxaluria Center | Rochester | Minnesota | 55905 | — |
| University of Missouri Healthcare | Columbia | Missouri | 65211 | — |
| Montana Medical Research, Inc | Missoula | Montana | 59808 | — |
| Sheldon J. Freedman, MD | Las Vegas | Nevada | 89144 | — |
| New York Presbyterian/Queens | Flushing | New York | 11355 | — |
| Long Island Gastrointestinal Research Group | Great Neck | New York | 11023 | — |
| New York University School of Medicine- Langone Medical Center | New York | New York | 10016 | — |
| University of Rochester | Rochester | New York | 14620 | — |
| University of North Carolina (UNC) - Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Duke University Medical Center | Durham | North Carolina | 27516 | — |
| Associated Urologists of North Carolina | Raleigh | North Carolina | 27612 | — |
| University of Cincinnati (UC) - Department of Nephrologyv | Cincinnati | Ohio | 45267 | — |
| Ohio State University (OSU)-Renal Division | Columbus | Ohio | 43210 | — |
| Clinical Research Solutions- Middleburg Heights | Middleburg Heights | Ohio | 44130 | — |
| Genito-Urinary Surgeons | Toledo | Ohio | 43606 | — |
| Oregon Health and Science University (OHSU) | Portland | Oregon | 97239 | — |
| Northeast Clinical Research Center | Bethlehem | Pennsylvania | 18017 | — |
| Lifespan Physician Group Minimally Invasive Urology Institute | Providence | Rhode Island | 02916 | — |
| Carolina Urologic Research Center | Myrtle Beach | South Carolina | 29572 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37212 | — |
| Accelemed Research Institute | Austin | Texas | 78745 | — |
| Renal Disease Research Institute | Dallas | Texas | 75246 | — |
| Houston Metro Urology | Houston | Texas | 77027 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229-3900 | — |
| Urology San Antonio Research | San Antonio | Texas | 78229 | — |
| Baylor Scott and White Research Institute- Temple | Temple | Texas | 76508 | — |
| Virginia Urology | Richmond | Virginia | 23235 | — |
| Urology of Virginia | Virginia Beach | Virginia | 23462 | — |
| University of Wisconsin - Division of Nephrology | Madison | Wisconsin | 53705 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 49 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03847090, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 10, 2022 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03847090 live on ClinicalTrials.gov.