This Study Tests Whether BI 425809 Together With Brain Training Using a Computer Improves Mental Functioning in Patients With Schizophrenia
Public ClinicalTrials.gov record NCT03859973. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Randomized, Double-blinded, Placebo-controlled Parallel Group Trial to Examine the Efficacy and Safety of BI 425809 Once Daily With Adjunctive Computerized Cognitive Training Over 12 Week Treatment Period in Patients With Schizophrenia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a study in adults with schizophrenia. The study tests whether a medicine called BI 425809 together with brain training improves mental abilities. Participants take study medication once a day for 12 weeks. At the start of the study, the participants are put into 2 groups. It is decided by chance who gets into which group. One group gets BI 425809 tablets every day. The other group gets placebo tablets every day. Placebo tablets look like the BI 425809 tablets, but contain no medicine. During the study, all participants do brain training using a computer. The doctors regularly test mental abilities of the participants. The results of the mental ability tests are compared between the groups. The doctors also check the general health of the patients.
Study identification
- NCT ID
- NCT03859973
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 200 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 50 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 15, 2019 (Actual)
- Primary completion
- Sep 30, 2022 (Actual)
- Completion
- Nov 4, 2022 (Actual)
- Last update posted
- Nov 18, 2023
2019 – 2022
United States locations
- U.S. sites
- 28
- U.S. states
- 13
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Atria Clinical Research | Little Rock | Arkansas | 72209 | — |
| Woodland Research Northwest | Rogers | Arkansas | 72758 | — |
| Encino Hospital Medical Center | Encino | California | 91436 | — |
| Collaborative Neuroscience Network, LLC (CNS) | Garden Grove | California | 92845 | — |
| Synergy San Diego | Lemon Grove | California | 91945 | — |
| Catalina Research Institute, LLC | Montclair | California | 91763 | — |
| Pacific Research Partners, LLC | Oakland | California | 94607 | — |
| NRC Research Institute | Orange | California | 92868 | — |
| CNRI - Los Angeles | Pico Rivera | California | 90660 | — |
| CNRI-San Diego, LLC | San Diego | California | 92102 | — |
| Collaborative Neuroscience Network, LLC (CNS) | Torrance | California | 90502 | — |
| Meridien Research | Maitland | Florida | 32751 | — |
| Premier Clinical Research Institute | Miami | Florida | 33122 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Apalachee Center | Tallahassee | Florida | 32308 | — |
| Jerome Golden Center for Behavioral Health | West Palm Beach | Florida | 33407 | — |
| Synexus | Atlanta | Georgia | 30328 | — |
| Uptown Research Institute | Chicago | Illinois | 60640 | — |
| Lake Charles Clinical Trials LLC | Lake Charles | Louisiana | 70629 | — |
| Cherry Health | Grand Rapids | Michigan | 49503 | — |
| Center for Behavioral Medicine | Kansas City | Missouri | 64108 | — |
| Synexus Clinical Research US, Inc. | New York | New York | 10017 | — |
| UNC Center for Excellence in Community Mental Health, North Carolina Psychiatric Research Center | Raleigh | North Carolina | 27608 | — |
| Midwest Clinical Research | Dayton | Ohio | 45417 | — |
| FutureSearch Trials of Dallas, LP | Dallas | Texas | 75231 | — |
| Pillar Clinical Research, LLC | Richardson | Texas | 75080 | — |
| Office of Dr. Aqeel Hashmi, MD, PA | Richmond | Texas | 77407 | — |
| Northwest Clinical Research Center | Bellevue | Washington | 98007 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 22 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03859973, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 18, 2023 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03859973 live on ClinicalTrials.gov.