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Recruiting Not applicable Interventional

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

ClinicalTrials.gov ID: NCT03860883

Public ClinicalTrials.gov record NCT03860883. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Sep 1, 2026, 11:04 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Melanoma Margins Trial-II - A Phase III, Multi-centre Randomised Controlled Trial Investigating 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma (02.18 MelMarT-II)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Patients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin. There is evidence that less radical margins of excision may be just as safe. This is a randomised controlled trial of 1 cm versus 2 cm margin of excision of the primary lesion for adult patients with stage II primary invasive cutaneous melanomas (AJCC 8th edition) to determine differences in disease-free survival. A reduction in margins is expected to improve patient quality of life.

Study identification

NCT ID
NCT03860883
Recruitment status
Recruiting
Study type
Interventional
Phase
Not applicable
Enrollment
2,998 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 16, 2019
Primary completion
Dec 30, 2029
Completion
Dec 30, 2034
Last update posted
Nov 26, 2024

2019 – 2034

United States locations

U.S. sites
128
U.S. states
32
U.S. cities
102
Facility City State ZIP Site status
University of South Alabama Mitchell Cancer Institute Mobile Alabama 36604 Recruiting
Banner MD Anderson Cancer Center Gilbert Arizona 85234 Recruiting
Mayo Clinic Phoenix Phoenix Arizona 85054 Recruiting
University of Arkansas for Medical Sciences Little Rock Arkansas 72205 Recruiting
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care Irvine California 92868 Recruiting
Los Angeles General Medical Center Los Angeles California 90033 Recruiting
USC Norris Comprehensive Cancer Center Los Angeles California 90033 Recruiting
The Angeles (Cedars-Sinai Medical Center and its Affiliates) Los Angeles California 90048-1804 Recruiting
UC Irvine Health - Chao Family Comprehensive Cancer Center Orange California 92868 Recruiting
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care Orange California 92868 Recruiting
Stanford Cancer Institute Palo Alto California 94304 Recruiting
Huntington Memorial Hospital Pasadena California 91105 Recruiting
Stanford Cancer Center South Bay San Jose California 95124 Recruiting
Kaiser Permanente - Vallejo Medical Center Vallejo California 94589 Recruiting
Kaiser Permanente - Walnut Creek Medical Center Walnut Creek California 94596 Recruiting
Smilow Hospital Care Center, Guilford Guilford Connecticut 06437 Recruiting
Yale University New Haven Connecticut 06520 Recruiting
MedStar Georgetown University Hospital Washington D.C. District of Columbia 20007 Recruiting
MedStar Washington Hospital Center Washington D.C. District of Columbia 20010 Recruiting
University of Miami Sylvester Comprehensive Cancer Center at Aventura Aventura Florida 33180 Recruiting
University of Miami Sylvester Comprehensive Cancer Center at Coral Gables Coral Gables Florida 33146 Recruiting
University of Miami Sylvester Cancer Center at Coral Springs Coral Springs Florida 33065 Recruiting
University of Miami Sylvester Comprehensive Center at Deerfield Beach Deerfield Beach Florida 33442 Recruiting
University of Miami Sylvester Comprehensive Center at Hollywood Hollywood Florida 33021 Recruiting
Baptist MD Anderson Cancer Center Jacksonville Florida 32207 Recruiting
Mayo Clinic in Florida Jacksonville Florida 32224 Recruiting
Lakeland Regional Health Hollis Cancer Center Lakeland Florida 33805 Recruiting
University of Miami Miller School of Medicine-Sylvester Cancer Centre Miami Florida 33136 Recruiting
University of Miami Comprehensive Cancer Center at Kendall Miami Florida 33176 Recruiting
University of Miami Comprehensive Cancer Center at Plantation Plantation Florida 33324 Recruiting
Moffitt Cancer Center - McKinley Campus Tampa Florida 33612 Recruiting
Moffitt Cancer Center, Magnolia Campus Tampa Florida 33612 Recruiting
Emory University Hospital Midtown Atlanta Georgia 30308 Recruiting
Emory University Atlanta Georgia 30322 Recruiting
Emory Saint Joseph's Hospital Atlanta Georgia 30342 Recruiting
Northside Hospital Atlanta Atlanta Georgia 30342 Recruiting
Northside Hospital Cancer Institute Atlanta Georgia 30342 Not yet recruiting
Nancy N and JC Lewis Cancer & Research Pavilion St. Joseph's/Candler Savannah Georgia 31405 Recruiting
Advocate Illinois Masonic Medical Center Chicago Illinois 60657 Recruiting
Northwestern Medicine Cancer Center Kishwaukee DeKalb Illinois 60115 Recruiting
Northwestern University Evanston Illinois 60208 Recruiting
Northwestern Medicine Cancer Center Delnor Geneva Illinois 60134 Recruiting
Northwestern Medicine Cancer Center Lake Forest Hospital Lake Forest Illinois 60045 Recruiting
Advocate Lutheran General Hospital Park Ridge Illinois 60068 Recruiting
Northwestern Medicine Cancer Center Warrenville Warrenville Illinois 60555 Recruiting
Indiana University - Melvin and Bren Simon Cancer Center Indianapolis Indiana 46202 Recruiting
Indiana University Melvin and Bren Simon Comprehensive Cancer Center Indianapolis Indiana 46202 Recruiting
Franciscan Health Indianapolis Indianapolis Indiana 46237 Recruiting
University of Kansas Hospital - Indian Creek Campus Overland Park Kansas 66211 Recruiting
University of Kansas Hospital- Westwood Cancer Center Westwood Kansas 66205 Recruiting
University of Kentucky Lexington Kentucky 40506 Recruiting
MedStar Franklin Square Medical Center Baltimore Maryland 21237 Recruiting
University of Michigan Medical Center Ann Arbor Michigan 48109 Recruiting
University of Michigan - Brighton Center for Specialty Care Brighton Michigan 48116 Recruiting
Mercy Health Saint Mary's Grand Rapids Michigan 49503 Recruiting
Spectrum Health at Butterworth Campus Grand Rapids Michigan 49503 Recruiting
West Michigan Cancer Centre Kalamazoo Michigan 49007 Recruiting
Siteman Cancer Centre, Barnes Jewish West County Creve Coeur Missouri 63141 Recruiting
University of Kansas Cancer Center Kansas City Missouri 64154 Recruiting
Cox South Hospital Springfield Missouri 65807 Recruiting
Washington University School of Medicine St Louis Missouri 63110 Recruiting
Nebraska Medicine - Bellevue Bellevue Nebraska 68123 Recruiting
Nebraska Medicine-Village Pointe Omaha Nebraska 68118 Recruiting
University of Nebraska Medicine Omaha Nebraska 68198 Recruiting
Cooperman Barnabas Medical Center Livingston New Jersey 07039 Recruiting
Rutgers Cancer Institute of New Jersey Piscataway New Jersey 08854 Recruiting
Lovelace Medical Centre-Saint Joseph Square Albuquerque New Mexico 87110 Recruiting
Lovelace Women's Hospital Albuquerque New Mexico 87110 Recruiting
Northwell Health Imbert Cancer Center Bay Shore New York 11706 Recruiting
Roswell Park Cancer Institute Buffalo New York 14203 Recruiting
Northwell Health/Center for Advanced Medicine Lake Success New York 11042 Recruiting
NYU Langone Medical Center (Winthrop Hospital) Mineola New York 11501 Recruiting
Northern Westchester Hospital Mount Kisco New York 10549 Recruiting
Laura & Isaac Perlmutter Cancer Center at NYU Langone Health New York New York 10016 Recruiting
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center New York New York 10032 Recruiting
Memorial Sloan Kettering Cancer Center New York New York 10065 Recruiting
Vassar Brothers Medical Center Poughkeepsie New York 12601 Recruiting
University of Rochester Rochester New York 14642 Recruiting
Phelps Memorial Hospital Center Sleepy Hollow New York 10591 Recruiting
State University of New York Upstate Medical University Syracuse New York 13210 Recruiting
State University of New York Upstate Medical Center-Community Campus Syracuse New York 13215 Recruiting
Wilmont Cancer Institute at Webster Webster New York 14580 Recruiting
University of North Carolina at Chapel Hill Chapel Hill North Carolina 27599 Recruiting
Duke University Medical Center Durham North Carolina 27710 Recruiting
East Carolina University Greenville North Carolina 27858 Recruiting
University of North Carolina Hospitals - Hillsborough Campus Hillsborough North Carolina 27278 Recruiting
Sanford Broadway Medical Centre Fargo North Dakota 58102 Recruiting
Sanford Roger Maris Cancer Centre Fargo North Dakota 58102 Recruiting
University Hospitals Avon Health Center Avon Ohio 44011 Recruiting
Miami Valley Hospital South Centerville Ohio 45459 Recruiting
University Hospitals Geauga Medical Center Chardon Ohio 44024 Recruiting
University of Cincinnati Cincinnati Ohio 45219 Recruiting
University Hospitals Cleveland Medical Centre Cleveland Ohio 44106 Recruiting
Ohio State University Comprehensive Cancer Center Columbus Ohio 43210 Recruiting
University Hospitals Chagrin Highlands Medical Centre Orange Ohio 44122 Recruiting
West Chester Hospital (OH394) West Chester Ohio 45069 Recruiting
University Hospitals St. John Medical Center Westlake Ohio 44145 Recruiting
OUHSC Stephenson Cancer Center Oklahoma City Oklahoma 73104 Recruiting
Mercy Health Center - Oncology Hematology Oklahoma City Oklahoma 73120-8362 Recruiting
Kaiser Sunnyside Medical Center Clackamas Oregon 97015 Recruiting
Kaiser Permanente Northwest - Oncology Clinic Portland Oregon 97227 Recruiting
St. Luke's University Health Network - Allentown Cancer Center Allentown Pennsylvania 18104 Recruiting
St Luke's University Health Network, Bethlehem Campus Bethlehem Pennsylvania 18015 Recruiting
St Luke's University Health Network, Anderson Campus Easton Pennsylvania 18045 Recruiting
Fox Chase Cancer Center Philadelphia Pennsylvania 19111 Recruiting
St Luke's University Health Network Quakertown Campus Quakertown Pennsylvania 18951 Recruiting
St. Luke's University Health Network - Upper Bucks Quakertown Pennsylvania 18951 Recruiting
Guthrie Medical Group PC-Robert Packer Hospital Sayre Pennsylvania 18840 Recruiting
Medical University of South Carolina Charleston South Carolina 29425 Recruiting
Sanford Cancer Center Oncology Clinic Sioux Falls South Dakota 57105, Recruiting
Sanford USD Medical Center - Sioux Falls Sioux Falls South Dakota 57105, Recruiting
The University of Texas MD Anderson Cancer Center Houston Texas 77030 Recruiting
University of Texas Health Science Center at San Antonio San Antonio Texas 78284-7884 Recruiting
Intermountain Medical Center Murray Utah 84157 Recruiting
Huntsman Cancer Institute (The University of Utah) Salt Lake City Utah 84112 Recruiting
University of Vermont Medical Center Burlington Vermont 05401 Recruiting
University of Vermount and Sate Agricultural College Burlington Vermont 05405 Recruiting
University of Virginia Health System Charlottesville Virginia 22903 Recruiting
VCU Massey Cancer Center Peninsula Cancer Institute Newport News Virginia 23601 Recruiting
VCU Massey Cancer Center Richmond Virginia 23298 Recruiting
Carilion Roanoke Memorial Hospital Roanoke Virginia 24014 Recruiting
VCU Massey Cancer Center Affiliate Valley Health Winchester Virginia 22601 Recruiting
University of Winsconsin Carbone Cancer Center-Eastpark medical Center Madison Wisconsin 53718 Recruiting
University of Wisconsin Carbone Cancer Center Madison Wisconsin 53792 Recruiting
Marshfield Medical Center - Marshfield Marshfield Wisconsin 54449 Recruiting
Aurora St Luke's Medical Center Milwaukee Wisconsin 53215 Recruiting
Medical College of Wisconsin Milwaukee Wisconsin 53226 Recruiting
Marshfield Medical Center- Weston Weston Wisconsin 54476 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 62 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03860883, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 26, 2024 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03860883 live on ClinicalTrials.gov.

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