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Completed Phase 1Phase 2 Interventional

A Dose Escalation and Cohort Expansion Study of Subcutaneously-Administered Cytokine ALKS 4230 (Nemvaleukin Alfa) as a Single Agent and in Combination With Anti-PD-1 Antibody (Pembrolizumab) in Subjects With Select Advanced or Metastatic Solid Tumors (ARTISTRY-2)

ClinicalTrials.gov ID: NCT03861793

Public ClinicalTrials.gov record NCT03861793. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 12:12 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/2 Study of ALKS 4230 Administered Subcutaneously as Monotherapy and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors - ARTISTRY-2 (001)

Study identification

NCT ID
NCT03861793
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Mural Oncology, Inc
Industry
Enrollment
116 participants

Conditions and interventions

Interventions

  • ALKS 4230 Biological
  • Pembrolizumab Biological

Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 25, 2019
Primary completion
Feb 28, 2023
Completion
Feb 28, 2023
Last update posted
Mar 4, 2024

2019 – 2023

United States locations

U.S. sites
17
U.S. states
16
U.S. cities
16
Facility City State ZIP Site status
Mural Oncology Investigational Site Los Angeles California 90025
Mural Oncology Investigational Site Los Angeles California 90211
Mural Oncology Investigational Site Washington D.C. District of Columbia 20007
Mural Oncology Investigational Site Atlanta Georgia 30322
Mural Oncology Investigational Site Chicago Illinois 60612
Mural Oncology Investigational Site Bethesda Maryland 20817
Mural Oncology Investigational Site Detroit Michigan 48201
Mural Oncology Investigational Site Saint Paul Minnesota 55101
Mural Oncology Investigational Site Morristown New Jersey 07962
Mural Oncology Investigational Site Buffalo New York 14263
Mural Oncology Investigational Site Huntersville North Carolina 28078
Mural Oncology Investigational Site Cincinnati Ohio 45229
Mural Oncology Investigational Site Philadelphia Pennsylvania 19111
Mural Oncology Investigational Site Charleston South Carolina 29425
Mural Oncology Investigational Site Houston Texas 77030
Mural Oncology Investigational Site Salt Lake City Utah 84119
Mural Oncology Investigational Site Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 31 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03861793, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 4, 2024 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03861793 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →