A Phase 2b Study of Inhaled RVT-1601 for the Treatment of Persistent Cough in IPF
Public ClinicalTrials.gov record NCT03864328. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging, Efficacy and Safety Study With Inhaled RVT-1601 for the Treatment of Persistent Cough in Patients With Idiopathic Pulmonary Fibrosis (IPF): SCENIC Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Idiopathic pulmonary fibrosis (IPF) is a rare, progressive life-threatening disease that is characterized by exertional dyspnea and persistent dry cough. Cough in IPF is both a presenting and a complicating clinical feature, which affects approximately three quarters of IPF cases. It is often a debilitating symptom that adversely affects quality of life (QoL) and is usually refractory to medical therapy. Inhaled RVT-1601 (formerly, PA101B), a new inhalation formulation of cromolyn sodium delivered via the eFlow® Closed System (CS) nebulizer, is being evaluated in this Phase 2b study for the treatment of persistent cough in patients with IPF.
Study identification
- NCT ID
- NCT03864328
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 108 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 89 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 29, 2019 (Actual)
- Primary completion
- May 29, 2020 (Actual)
- Completion
- Jun 5, 2020 (Actual)
- Last update posted
- Jun 11, 2020
2019 – 2020
United States locations
- U.S. sites
- 28
- U.S. states
- 21
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama | Birmingham | Alabama | 35294 | — |
| University of California Davis | Sacramento | California | 95817 | — |
| University California San Francisco | San Francisco | California | 94143 | — |
| National Jewish Health | Denver | Colorado | 80206 | — |
| Ascension Medical Group / St. Vincent's Lung Institute | Jacksonville | Florida | 32204 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Tampa General Hospital / Uni of South Florida | Tampa | Florida | 33606 | — |
| Loyola University | Maywood | Illinois | 60153 | — |
| Tulane University | New Orleans | Louisiana | 70112 | — |
| Johns Hopkins University School of Medicine | Baltimore | Maryland | 21224 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Universty of Michigan | Ann Arbor | Michigan | 48109 | — |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55905 | — |
| St. Luke's Hospital | Chesterfield | Missouri | 63017 | — |
| Cornell University Weill Cornell Medical College | New York | New York | 10065 | — |
| American Health Research | Charlotte | North Carolina | 28207 | — |
| Duke University | Durham | North Carolina | 27710 | — |
| Pulmonix, LLC | Greensboro | North Carolina | 27403 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Temple University School of Medicine | Philadelphia | Pennsylvania | 19140 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Spartanburg Medical Research | Spartanburg | South Carolina | 29303 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| UT Southwester Medical Center | Dallas | Texas | 75390 | — |
| University of Utah Hospitals & Clinics | Salt Lake City | Utah | 84103 | — |
| University of Virginia | Charlottesville | Virginia | 22903 | — |
| University of Washington School of Medicine | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 53 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03864328, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 11, 2020 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03864328 live on ClinicalTrials.gov.