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Completed Phase 3 Interventional Results available

A Study to Evaluate SAGE-217 in Adult Participants With Major Depressive Disorder (MDD)

ClinicalTrials.gov ID: NCT03864614

Public ClinicalTrials.gov record NCT03864614. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 11, 2026, 12:43 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Open-Label, 1-Year Study of the Safety, Tolerability, and Need for Re-Treatment With SAGE-217 in Adult Subjects With Major Depressive Disorder

Study identification

NCT ID
NCT03864614
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Biogen
Industry
Enrollment
1,515 participants

Conditions and interventions

Interventions

  • SAGE-217 Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 26, 2019
Primary completion
Jun 21, 2023
Completion
Jun 21, 2023
Last update posted
Aug 26, 2024

2019 – 2023

United States locations

U.S. sites
52
U.S. states
20
U.S. cities
46
Facility City State ZIP Site status
Sage Investigational Site Dothan Alabama 36303
Sage Investigational Site Phoenix Arizona 85012
Sage Investigational Site Anaheim California 92805
Sage Investigational Site Costa Mesa California 92626
Sage Investigational Site Glendale California 91206
Sage Investigational Site Irvine California 92614
Sage Investigational Site Los Alamitos California 90720
Sage Investigational Site Oceanside California 92056
Sage Investigational Site Orange California 92868
Sage Investigational Site Riverside California 92503
Sage Investigational Site San Diego California 92103
Sage Investigational Site Temecula California 92591
Sage Investigational Site Colorado Springs Colorado 80910
Sage Investigational Site Cromwell Connecticut 06416
Sage Investigational Site Norwich Connecticut 06360
Sage Investigational Site Coral Springs Florida 33067
Sage Investigational Site Jacksonville Florida 32256
Sage Investigational Site Miami Florida 33122
Sage Investigational Site Orlando Florida 32801
Sage Investigational Site Orlando Florida 32807
Sage Investigational Site Pensacola Florida 32502
Sage Investigational Site Alpharetta Georgia 30022
Sage Investigational Site Atlanta Georgia 30331
Sage Investigational Site Marietta Georgia 30060
Sage Investigational Site Savannah Georgia 31405
Sage Investigational Site Chicago Illinois 60634
Sage Investigational Site Chicago Illinois 60640
Sage Investigational Site Watertown Massachusetts 02472
Sage Investigational Site Ann Arbor Michigan 48109
Sage Investigational Site Saint Charles Missouri 63304
Sage Investigational Site Lincoln Nebraska 68526
Sage Investigational Site Cherry Hill New Jersey 08002
Sage Investigational site Marlton New Jersey 08053
Sage Investigational Site Princeton New Jersey 08540
Sage Investigational Site Albuquerque New Mexico 87109
Sage Investigational Site Brooklyn New York 11229
Sage Investigational Site Brooklyn New York 11235
Sage Investigational Site Mount Kisco New York 10549
Sage Investigational Site Beachwood Ohio 44122
Sage Investigational Site Cincinnati Ohio 45212
Sage Investigational site Cincinnati Ohio 45215
Sage Investigational Site Cincinnati Ohio 45219
Sage Investigational Site North Canton Ohio 44720
Sage Investigational Site Oklahoma City Oklahoma 73112
Sage Investigational Site Plymouth Meeting Pennsylvania 19462
Sage Investigational Site Austin Texas 78759
Sage Investigational Site Dallas Texas 75231
Sage Investigational Site Houston Texas 77030
Sage Investigational Site Houston Texas 77081
Sage Investigational Site Newport Texas 78712
Sage Investigational Site Wichita Falls Texas 76309
Sage Investigational Site Bellevue Washington 98007

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03864614, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 26, 2024 · Synced May 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03864614 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →