Trial of ARV-110 in Patients With Metastatic Castration Resistant Prostate Cancer
Public ClinicalTrials.gov record NCT03888612. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2, Open-label, Dose Escalation, and Cohort Expansion Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ARV-110 in Patients With Metastatic Castration Resistant Prostate Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Phase 1/2 dose escalation study to assess the safety and tolerability of ARV-110 in men with mCRPC who have progressed on prior approved systemic therapies for their castrate resistant disease (one of which must be enzalutamide or abiraterone).
Study identification
- NCT ID
- NCT03888612
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 248 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 1, 2019 (Actual)
- Primary completion
- Apr 29, 2024 (Actual)
- Completion
- Jan 27, 2025 (Actual)
- Last update posted
- Apr 1, 2025
2019 – 2025
United States locations
- U.S. sites
- 54
- U.S. states
- 14
- U.S. cities
- 54
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Trial Site | Los Angeles | California | 90095 | — |
| Clinical Trial Site | Orange | California | 92868 | — |
| Clinical Trial Site | San Francisco | California | 94158 | — |
| Clinical Trial Site | New Haven | Connecticut | 06510 | — |
| Clinical Trial Site | Altamonte Springs | Florida | 32701 | — |
| Clinical Trial Site | Bonita Springs | Florida | 34135 | — |
| Clinical Trial Site | Bradenton | Florida | 34211 | — |
| Clinical Trial Site | Brandon | Florida | 33511 | — |
| Clinical Trial Site | Cape Coral | Florida | 33939 | — |
| Clinical Trial Site | Clearwater | Florida | 33761 | — |
| Clinical Trial Site | Daytona Beach | Florida | 32117 | — |
| Clinical Trial Site | Fleming Island | Florida | 32003 | — |
| Clinical Trial Site | Fort Myers | Florida | 33908 | — |
| Clinical Trial Site | Gainesville | Florida | 32605 | — |
| Clinical Trial Site | Largo | Florida | 33770 | — |
| Clinical Trial Site | Lecanto | Florida | 34461 | — |
| Clinical Trial Site | Naples | Florida | 34102 | — |
| Clinical Trial Site | New Port Richey | Florida | 34655 | — |
| Clinical Trial Site | Ocala | Florida | 34474 | — |
| Clinical Trial Site | Orange City | Florida | 32763 | — |
| Clinical Trial Site | Orlando | Florida | 32806 | — |
| Clinical Trial Site | Port Charlotte | Florida | 33980 | — |
| Clinical Trial Site | Sarasota | Florida | 34236 | — |
| Clinical Trial Site | Spring Hill | Florida | 34608 | — |
| Clinical Trial Site | St. Petersburg | Florida | 33705 | — |
| Clinical Trial Site | Stuart | Florida | 34994 | — |
| Clinical Trial Site | Tampa | Florida | 33607 | — |
| Clinical Trial Site | Tavares | Florida | 32778 | — |
| Clinical Trial Site | The Villages | Florida | 32159 | — |
| Clinical Trial Site | Venice | Florida | 34292 | — |
| Clinical Trial Site | Vero Beach | Florida | 32960 | — |
| Clinical Trial Site | Wellington | Florida | 33414 | — |
| Clinical Trial Site | West Palm Beach | Florida | 33401 | — |
| Clinical Trial Site | Winter Park | Florida | 32792 | — |
| Clinical Trial Site | Chicago | Illinois | 60611 | — |
| Clinical Trial Site | New Orleans | Louisiana | 70112 | — |
| Clinical Trial Site | Boston | Massachusetts | 02114 | — |
| Clinical Trial Site | Detroit | Michigan | 48201 | — |
| Clinical Trial Site | Omaha | Nebraska | 68130 | — |
| Clinical Trial Site | Las Vegas | Nevada | 89169 | — |
| Clinical Trial Site | New York | New York | 10065 | — |
| Clinical Trial Site | Portland | Oregon | 97239 | — |
| Clinical Trial Site | Dickson | Tennessee | 37055 | — |
| Clinical Trial Site | Franklin | Tennessee | 37067 | — |
| Clinical Trial Site | Gallatin | Tennessee | 37066 | — |
| Clinical Trial Site | Hendersonville | Tennessee | 37075 | — |
| Clinical Trial Site | Hermitage | Tennessee | 37076 | — |
| Clinical Trial Site | Lebanon | Tennessee | 37090 | — |
| Clinical Trial Site | Murfreesboro | Tennessee | 37129 | — |
| Clinical Trial Site | Nashville | Tennessee | 37211 | — |
| Clinical Trial Site | Shelbyville | Tennessee | 37160 | — |
| Clinical Trial Site | Smyrna | Tennessee | 37167 | — |
| Clinical Trial Site | Salt Lake City | Utah | 84112 | — |
| Clinical Trial Site | Charlottesville | Virginia | 22903 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03888612, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 1, 2025 · Synced Nov 4, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03888612 live on ClinicalTrials.gov.