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Completed Phase 1 Interventional

A Study of MEDI5395 in Combination With Durvalumab in Participants With Select Advanced Solid Tumors

ClinicalTrials.gov ID: NCT03889275

Public ClinicalTrials.gov record NCT03889275. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 4, 2026, 2:15 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-label Phase 1 Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of MEDI5395 in Combination With Durvalumab in Subjects With Select Advanced Solid Tumors.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The reason for the study is to find out if MEDI5395 and durvalumab will work and be safe for the treatment of solid tumors.

Study identification

NCT ID
NCT03889275
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
MedImmune LLC
Industry
Enrollment
39 participants

Conditions and interventions

Interventions

Biological

Eligibility (public fields only)

Age range
18 Years to 101 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 23, 2019
Primary completion
Nov 18, 2021
Completion
Dec 11, 2022
Last update posted
Feb 20, 2023

2019 – 2022

United States locations

U.S. sites
8
U.S. states
7
U.S. cities
8
Facility City State ZIP Site status
Research Site Phoenix Arizona 85054
Research Site La Jolla California 92093
Research Site Rochester Minnesota 55905
Research Site Buffalo New York 14263
Research Site New York New York 10065
Research Site Chapel Hill North Carolina 27599
Research Site Pittsburgh Pennsylvania 15232
Research Site Providence Rhode Island 02903

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03889275, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 20, 2023 · Synced Sep 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03889275 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →