ClinicalTrials.gov record
Study of Cilofexor in Adults With Primary Sclerosing Cholangitis
ClinicalTrials.gov ID: NCT03890120
Public ClinicalTrials.gov record NCT03890120. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, and Efficacy of Cilofexor in Non-Cirrhotic Subjects With Primary Sclerosing Cholangitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to evaluate whether cilofexor reduces the risk of fibrosis progression among non-cirrhotic adults with primary sclerosing cholangitis (PSC).
Study identification
- NCT ID
- NCT03890120
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 419 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 27, 2019 (Actual)
- Primary completion
- Nov 10, 2022 (Actual)
- Completion
- Dec 23, 2022 (Actual)
- Last update posted
- Nov 29, 2023
2019 – 2022
United States locations
- U.S. sites
- 82
- U.S. states
- 32
- U.S. cities
- 68
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Institute For Liver Health | Glendale | Arizona | 85306 | — |
| The Institute for Liver Heath | Phoenix | Arizona | 85013 | — |
| Southern California Research Center | Coronado | California | 92118 | — |
| Altman Clinical and Translational Research Institute (Clinic) | La Jolla | California | 92037 | — |
| Scripps Clinic/Green Hospital | La Jolla | California | 92037 | — |
| Ruane Clinical Research Group Inc. | Los Angeles | California | 90036 | — |
| Stanford Hospital | Palo Alto | California | 94025 | — |
| California Liver Research Institute | Pasadena | California | 91105 | — |
| University of California, Davis Medical Center (study visits) | Sacramento | California | 95817 | — |
| Sutter Pacific Medical Foundation - California Pacific Medical Center | San Francisco | California | 94107 | — |
| University of California, San Francisco Liver Clinic | San Francisco | California | 94143 | — |
| Cedars Sinai Medical Center | West Hollywood | California | 90048 | — |
| University of Colorado Denver and Hospital | Aurora | Colorado | 80045 | — |
| Peak Gastroenterology Associates | Colorado Springs | Colorado | 80907 | — |
| South Denver Gastroenterology, PC | Englewood | Colorado | 80113 | — |
| Yale School of Medicine | New Haven | Connecticut | 48109 | — |
| MedStar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| Schiff Center for Liver Diseases/University of Miami | Miami | Florida | 33136 | — |
| Advanced Research Institute, Inc | New Port Richey | Florida | 34653 | — |
| Advanced Medical Research Center | Port Orange | Florida | 32127 | — |
| Cleveland Clinic Florida | Weston | Florida | 33331 | — |
| Piedmont Atlanta Hospital | Atlanta | Georgia | 30309 | — |
| Northwestern Memorial Hospital; Clinical Research Unit | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of Chicago Medical Center (outpatient clinic) | Chicago | Illinois | 60637 | — |
| NorthShore University Healthsystem | Evanston | Illinois | 60201 | — |
| IU Health University Hospital | Indianapolis | Indiana | 46202 | — |
| University of Kansas Hospital | Kansas City | Kansas | 66160 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| Louisiana Research Center, LLC | Shreveport | Louisiana | 71105 | — |
| Mercy Medical Center | Baltimore | Maryland | 21202 | — |
| Walter Reed National Military Medical Center | Bethesda | Maryland | 20889 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| NECCR PrimaCare Research, LLC | Fall River | Massachusetts | 02721 | — |
| Michigan Medicine - University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Minnesota Gastroenterology, PA | Maplewood | Minnesota | 55117 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Southern Therapy and Advanced Research LLC | Jackson | Mississippi | 39157 | — |
| Saint Louis University, Gastroenterology & Hepatology | St Louis | Missouri | 63104 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68105 | — |
| Rutgers New Jersey Medical School - Doctors Office Center | Newark | New Jersey | 07103 | — |
| Northwell Health Center for Liver Diseases and Transplantation | Manhasset | New York | 11030 | — |
| NYU Langone Health | New York | New York | 10016 | — |
| Weill Cornell Medical College | New York | New York | 10021 | — |
| Icahn School of Medicine at Mount Sinai Beth Israel | New York | New York | 10029 | — |
| Mount Sinai Medical Center | New York | New York | 10029 | — |
| Center for Liver Disease and Transplantation, Columbia University Medical Center | New York | New York | 10032 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| The University of NC at Chapel Hill, Clinical and Translational Research Center (CTRC) | Chapel Hill | North Carolina | 27599 | — |
| Carolinas Medical Center - Center for Liver Disease | Charlotte | North Carolina | 28204 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Wake Forest Baptist Health | Winston-Salem | North Carolina | 27157 | — |
| Holmes Hospital | Cincinnati | Ohio | 45267 | — |
| Penn State Health Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Einstein Medical Center | Philadelphia | Pennsylvania | 19141 | — |
| Reading Hospital | West Reading | Pennsylvania | 19611 | — |
| University Gastroenterology | Providence | Rhode Island | 02905 | — |
| Medical University of South Carolina | Charleston | South Carolina | 28204 | — |
| Rapid City Medical Center, LLP | Rapid City | South Dakota | 57701 | — |
| Methodist University Hospital | Memphis | Tennessee | 38104 | — |
| Vanderbilt University Medical Center - Digestive Disease Center | Nashville | Tennessee | 37232 | — |
| Texas Clinical Research Institute | Arlington | Texas | 76012 | — |
| The Liver Institute at Methodist Dallas Medical Center | Dallas | Texas | 75203 | — |
| Annette & Harold C. Simmons Transplant Institute @ Baylor University Medical Center at Dallas | Dallas | Texas | 75246 | — |
| Baylor Scott & White Medical Center at Fort Worth | Fort Worth | Texas | 76104 | — |
| Baylor College of Medicine - Advanced Liver Therapies | Houston | Texas | 77030 | — |
| Spring Gastroenterology Associates | Humble | Texas | 77338 | — |
| San Antonio Military Medical Center, Gastro/Hepatology | San Antonio | Texas | 78234 | — |
| Intermountain Medical Center - Transplant Services | Murray | Utah | 84107 | — |
| University of Utah Hospital | Salt Lake City | Utah | 84132 | — |
| The University of Vermont Medical Center | Burlington | Vermont | 05401 | — |
| University of Virginia Medical Center | Charlottesville | Virginia | 22908 | — |
| Verity Research Inc. | Fairfax | Virginia | 22031 | — |
| Bon Secours Richmond Community Hospital | Richmond | Virginia | 23226 | — |
| Virginia Commonwealth University Clinical Research Services Unit | Richmond | Virginia | 23298 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
| Liver Institute Northwest | Seattle | Washington | 98105 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 119 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03890120, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 29, 2023 · Synced Nov 1, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03890120 live on ClinicalTrials.gov.