Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study
Public ClinicalTrials.gov record NCT03901807. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Prospective, Multicenter, Randomized, Open-Label Study to Evaluate the Efficacy and Safety of PMX Cartridge in Addition to Standard Medical Care for Patients With Endotoxemic Septic Shock
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Prospective, multicenter, randomized, open-label study of standard of care plus the PMX cartridge versus standard of care alone in patients with endotoxemic septic shock
Study identification
- NCT ID
- NCT03901807
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 157 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 9, 2020 (Actual)
- Primary completion
- May 8, 2025 (Actual)
- Completion
- Feb 10, 2026 (Actual)
- Last update posted
- Oct 13, 2026
2020 – 2026
United States locations
- U.S. sites
- 20
- U.S. states
- 16
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294-0111 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| University of California, San Francisco | San Francisco | California | 94143 | — |
| Pulmonary Associates | Boulder | Colorado | 80909 | — |
| George Washington University | Washington D.C. | District of Columbia | 20037 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Louisiana State University Health Shreveport | Shreveport | Louisiana | 71103 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01199 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Cooper Health System | Camden | New Jersey | 08103 | — |
| Rutgers, The State University of New Jersey | Piscataway | New Jersey | 08854 | — |
| Mt Sinai Hospital | New York | New York | 10029 | — |
| Stony Brook University | Stony Brook | New York | 11794 | — |
| UPMC | Pittsburgh | Pennsylvania | 15213 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| CHI Memorial | Chattanooga | Tennessee | 37404 | — |
| Parkridge Hospital | Chattanooga | Tennessee | 37404 | — |
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| Institute for Extracorporeal Life Support | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03901807, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 13, 2026 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03901807 live on ClinicalTrials.gov.